The average train between Pisa and Isernia takes 7h 23m and the fastest train takes 5h 19m. The train service runs several times per day from Pisa to Isernia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Pisa and Isernia. The earliest departure is at 9:15 AM in the morning, and the last departure from Pisa is at 8:38 PM which arrives into Isernia at 8:27 AM. All services require a transfer, and take on average 7h 23m. The schedules shown below are for the next available departures.
Want to know about travelling from Pisa to Isernia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Pisa to Isernia. However, there are services departing from Pisa Centrale station and arriving at Isernia station via Roma Termini station. The journey, including transfers, takes approximately 7h 23m.
Pisa to Isernia train services, operated by Trenitalia Frecce, depart from Pisa Centrale station.
Pisa to Isernia train services, operated by Trenitalia, arrive at Isernia station.
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The distance between Pisa and Isernia is 391.5 km. The road distance is 507 km.
You can take a train from Pisa Centrale to Isernia via Roma Termini in around 6h 4m.
