The average train between Pisa and Isernia takes 11h 57m and the fastest train takes 10h 37m. There is at least one train per day from Pisa to Isernia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run once daily between Pisa and Isernia. The earliest departure is at 9:15 AM in the morning, and the last departure from Pisa is at 8:38 PM which arrives into Isernia at 11:15 AM. All services require a transfer, and take on average 11h 57m. The schedules shown below are for the next available departures.
Want to know about travelling from Pisa to Isernia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Pisa to Isernia. However, there are services departing from Pisa station and arriving at Isernia station via Roma Tiburtina. The journey, including transfers, takes approximately 11h 57m.
Pisa to Isernia train services, operated by Trenitalia Frecce, depart from Pisa Centrale station.
Pisa to Isernia train services, operated by Trenitalia Frecce, arrive at Isernia station.
Book your Pisa to Isernia train tickets online with Trenitalia Frecce and Trenitalia.
The distance between Pisa and Isernia is 391.5 km. The road distance is 517 km.
You can take a train from Pisa Centrale to Isernia via Roma Tiburtina in around 5h 23m.
