The average train between Pisa and Rome takes 3h 22m and the fastest train takes 2h 21m. There is a train service every few hours from Pisa to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Pisa and Rome. The earliest departure is at 5:45 AM in the morning, and the last departure from Pisa is at 8:31 PM which arrives into Rome at 11:01 PM. All services run direct with no transfers required, and take on average 3h 22m. The schedules shown below are for the next available departures.
Want to know about travelling from Pisa to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
Yes, there is a direct train departing from Pisa station and arriving at Rome station. Services depart hourly, and operate 3 times a day. The journey takes approximately 3h 22m.
Pisa to Rome train services, operated by Trenitalia, depart from Pisa Centrale station.
Pisa to Rome train services, operated by Trenitalia, arrive at Roma Termini station.
Book your Pisa to Rome train tickets online with Trenitalia, Trenitalia Frecce and Trenitalia Intercity.
The distance between Pisa and Rome is 263.9 km. The road distance is 330 km.
Trenitalia Frecce operates a train from Pisa Centrale to Roma Termini every 4 hours. Tickets cost €45–95 and the journey takes 2h 52m. Two other operators also service this route.