The average bus between Pisa and Isernia takes 8h 49m and the fastest bus takes 7h 20m. There is at least one bus per day from Pisa to Isernia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Pisa and Isernia. The earliest departure is at 12:25 AM at night, and the last departure from Pisa is at 1:25 PM which arrives into Isernia at 11:10 PM. All services require a transfer, and take on average 8h 49m. The schedules shown below are for the next available departures.
Want to know about travelling from Pisa to Isernia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Pisa to Isernia. However, there are services departing from Pisa station and arriving at Isernia station via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 8h 49m.
Pisa to Isernia bus services, operated by FlixBus, depart from Pisa station.
Pisa to Isernia bus services, operated by FlixBus, arrive at Isernia station.
Book your Pisa to Isernia bus tickets online with FlixBus and ATM Azienda di Trasporti Molisana S.p.A..
The distance between Pisa and Isernia is 391.5 km. The road distance is 529 km.
You can take a bus from Pisa to Isernia via Roma, Autostazione Tiburtina in around 8h 40m.
