The average train between Stuttgart and Isernia takes 18h 53m and the fastest train takes 13h 55m. The train service runs several times per day from Stuttgart to Isernia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Stuttgart and Isernia. The earliest departure is at 8:28 AM in the morning, and the last departure from Stuttgart is at 11:26 PM which arrives into Isernia at 7:55 PM. All services require a transfer at Singen and take an average of 18h 53m. The schedules shown below are for the next available departures.





13h 58m • 5 changes
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19h 59m • 5 changes
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20h 14m • 5 changes
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20h 29m • 5 changes





13h 55m • 5 changes
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19h 59m • 5 changes
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22h 7m • 5 changes
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20h 14m • 5 changes





13h 58m • 5 changes
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19h 59m • 5 changes
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22h 7m • 5 changes
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20h 14m • 5 changes





13h 58m • 5 changes
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19h 59m • 5 changes
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22h 7m • 5 changes
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21h 24m • 5 changes





13h 58m • 5 changes
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19h 59m • 5 changes
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22h 7m • 5 changes
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21h 24m • 5 changes
Want to know about travelling from Stuttgart to Isernia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Stuttgart to Isernia. However, there are services departing from Stuttgart station and arriving at Isernia station via Singen. The journey, including transfers, takes approximately 18h 53m.
Stuttgart to Isernia train services, operated by Deutsche Bahn Intercity (DB IC), depart from Hauptbahnhof station.
Stuttgart to Isernia train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Isernia station.
Book your Stuttgart to Isernia train tickets online with Deutsche Bahn Intercity (DB IC), Swiss Federal Railways (SBB CFF FFS) and 3 other operators.
The distance between Stuttgart and Isernia is 891.5 km. The road distance is 1,250 km.
You can take a train from Hauptbahnhof to Isernia via Singen, Zürich HB, Lugano, Milano Centrale, and Roma Termini in around 14h 51m.