The average train between Stuttgart and Isernia takes 23h 18m and the fastest train takes 17h 11m. The train service runs several times per day from Stuttgart to Isernia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Stuttgart and Isernia. The earliest departure is at 3:39 AM at night, and the last departure from Stuttgart is at 10:17 PM which arrives into Isernia at 10:26 PM. All services require a transfer at München Hbf and take an average of 23h 18m. The schedules shown below are for the next available departures.
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25h 11m • 5 changes
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25h 23m • 5 changes





17h 11m • 5 changes
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25h 11m • 5 changes
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24h 6m • 5 changes





18h 47m • 5 changes
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25h 11m • 5 changes
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24h 6m • 5 changes
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24h 9m • 5 changes
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25h 11m • 5 changes
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24h 6m • 5 changes
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24h 9m • 5 changes
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25h 11m • 5 changes
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24h 6m • 5 changes
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24h 9m • 5 changes
Want to know about travelling from Stuttgart to Isernia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Stuttgart to Isernia. However, there are services departing from Stuttgart station and arriving at Isernia station via München Hbf. The journey, including transfers, takes approximately 23h 18m.
Stuttgart to Isernia train services, operated by Deutsche Bahn Intercity (DB IC), depart from Hauptbahnhof station.
Stuttgart to Isernia train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Isernia station.
Book your Stuttgart to Isernia train tickets online with Deutsche Bahn Intercity (DB IC), Transdev GmbH and 6 other operators.
The distance between Stuttgart and Isernia is 891.5 km. The road distance is 1,323 km.
You can take a train from Hauptbahnhof to Isernia via München Hbf, Kufstein, Brennero - Brenner, Bolzano Bozen, and Roma Termini in around 16h 40m.