The average train between London and Isernia takes 26h 30m and the fastest train takes 22h 54m. There is at least one train per day from London to Isernia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run once daily between London and Isernia. The earliest departure is at 11:31 AM in the morning, and the last departure from London is at 8:01 PM which arrives into Isernia at 7:55 PM. All services require a transfer at Paris Nord and take an average of 26h 30m. The schedules shown below are for the next available departures.
Want to know about travelling from London to Isernia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from London to Isernia. However, there are services departing from London station and arriving at Isernia station via Paris Nord. The journey, including transfers, takes approximately 26h 30m.
London to Isernia train services, operated by Eurostar, depart from London St Pancras Intl station.
London to Isernia train services, operated by Eurostar, arrive at Isernia station.
Book your London to Isernia train tickets online with Eurostar, Société Nationale des Chemins de fer Français (SNCF) and 2 other operators.
The distance between London and Isernia is 1,550.6 km. The road distance is 2,093 km.
You can take a train from London St Pancras Intl to Isernia via Paris Nord, Paris Gare De Lyon, Milano Centrale, and Roma Termini in around 17h 5m.