Spoleto to Isernia Trains

Spoleto to Isernia trains

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Trip Overview

The average train between Spoleto and Isernia takes 5h 55m and the fastest train takes 3h 39m. The train service runs several times per day from Spoleto to Isernia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

5h 55m
Duration: 310 km
Distance: €44
Average price: 5 times a day
Frequency

Train (Trenitalia)

best

Take the train from Spoleto to Roma Terminitrain 4153 / ...
Take the train from Roma Termini to Iserniatrain Re

4h 49m

€35–64

Spoleto to Isernia train times

Trains run 5 times a day between Spoleto and Isernia. The earliest departure is at 7:17 AM in the morning, and the last departure from Spoleto is at 10:05 PM which arrives into Isernia at 8:27 AM. All services require a transfer, and take on average 5h 55m. The schedules shown below are for the next available departures.

Departing Sunday, October 18, 2026

7:17 AM → 11:15 AM
3h 58m • 1 change
12:33 PM → 4:40 PM
4h 7m • 1 change
3:00 PM → 7:55 PM
4h 55m • 1 change
4:14 PM → 10:23 PM
6h 9m • 1 change
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Departing Monday, October 19, 2026

7:36 AM → 11:15 AM
3h 39m • 1 change
9:38 AM → 3:23 PM
5h 45m • 1 change
11:24 AM → 4:40 PM
5h 16m • 1 change
5:05 PM → 10:26 PM
5h 21m • 1 change
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Departing Tuesday, October 20, 2026

7:36 AM → 11:15 AM
3h 39m • 1 change
9:38 AM → 3:23 PM
5h 45m • 1 change
11:24 AM → 4:40 PM
5h 16m • 1 change
5:05 PM → 10:26 PM
5h 21m • 1 change
Show more

Departing Wednesday, October 21, 2026

7:36 AM → 11:15 AM
3h 39m • 1 change
9:38 AM → 3:23 PM
5h 45m • 1 change
11:24 AM → 4:40 PM
5h 16m • 1 change
5:05 PM → 10:26 PM
5h 21m • 1 change
Show more

Departing Thursday, October 22, 2026

7:36 AM → 11:15 AM
3h 39m • 1 change
9:38 AM → 3:23 PM
5h 45m • 1 change
11:24 AM → 4:40 PM
5h 16m • 1 change
5:05 PM → 10:26 PM
5h 21m • 1 change
Show more

Departing Friday, October 23, 2026

7:36 AM → 11:15 AM
3h 39m • 1 change
9:38 AM → 3:23 PM
5h 45m • 1 change
11:24 AM → 4:40 PM
5h 16m • 1 change
5:05 PM → 10:26 PM
5h 21m • 1 change
Show more

Departing Saturday, October 24, 2026

7:36 AM → 11:15 AM
3h 39m • 1 change
9:38 AM → 3:23 PM
5h 45m • 1 change
11:24 AM → 4:40 PM
5h 16m • 1 change
5:05 PM → 10:26 PM
5h 21m • 1 change

Frequently asked questions

Want to know about travelling from Spoleto to Isernia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.