The train between Brussels and Isernia takes 32h 48m. The train runs, on average, once a week from Brussels to Isernia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run once a week between Brussels and Isernia. The service departs Brussels at 7:52 AM in the morning, which arrives into Isernia at 16:40:00. All services require a transfer at Chambery Challes Les Eaux and take an average of 32h 48m. The schedules shown below are for the next available departures.
Want to know about travelling from Brussels to Isernia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Brussels to Isernia. However, there are services departing from Brussel-Zuid / Bruxelles-Midi station and arriving at Isernia station via Chambery Challes Les Eaux station, Milano Centrale station and Roma Termini station. The journey, including transfers, takes approximately 32h 48m.
Brussels to Isernia train services, operated by Eurostar, depart from Brussel-Zuid / Bruxelles-Midi station.
Brussels to Isernia train services, operated by Trenitalia, arrive at Isernia station.
Book your Brussels to Isernia train tickets online with Omio.
The distance between Brussels and Isernia is 1277.2 km. The road distance is 1594 km.
You can take a train from Brussel-Zuid / Bruxelles-Midi to Isernia via Chambery Challes Les Eaux, Milano Centrale, and Roma Termini in around 15h 22m.
