The average train between L'Aquila and Isernia takes 8h 43m and the fastest train takes 6h 6m. The train service runs several times per day from L'Aquila to Isernia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between L'Aquila and Isernia. The earliest departure is at 7:41 AM in the morning, and the last departure from L'Aquila is at 8:23 PM which arrives into Isernia at 8:27 AM. All services require a transfer at Terni and take an average of 8h 43m. The schedules shown below are for the next available departures.


6h 6m • 2 changes


7h 59m • 2 changes
Arrives next day


12h 4m • 2 changes


6h 6m • 2 changes


7h 59m • 2 changes
Arrives next day


12h 4m • 2 changes


6h 6m • 2 changes


7h 59m • 2 changes
Arrives next day


12h 4m • 2 changes


6h 6m • 2 changes


7h 59m • 2 changes
Arrives next day


12h 4m • 2 changes
Want to know about travelling from L'Aquila to Isernia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from L'Aquila to Isernia. However, there are services departing from L'Aquila station and arriving at Isernia station via Terni. The journey, including transfers, takes approximately 8h 43m.
L'Aquila to Isernia train services, operated by Trenitalia, depart from L'aquila station.
L'Aquila to Isernia train services, operated by Trenitalia, arrive at Isernia station.
Book your L'Aquila to Isernia train tickets online with Trenitalia.
The distance between L'Aquila and Isernia is 108.6 km. The road distance is 380 km.
You can take a train from L'aquila to Isernia via Terni and Roma Termini in around 7h 3m.