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How to get fromPisa to Iserniaby train (Trenitalia), bus, car, plane or train

Find Transport to Isernia

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There are 8 ways to get from Pisa to Isernia by train (Trenitalia), bus, car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Pisa Centrale to Roma TiburtinatrainFa
    2. Take the train from Roma Tiburtina to IserniatrainRe
    5h 23m
    €48–81
  2. Bus

    cheapest
    1. Take the bus from Pisa to Cassinobus
    2. Take the bus from Cassino Piazza Garibaldi to IserniabusCb 015
    9h 24m
    €4–6
  3. Bus via Rome

    1. Take the bus from Pisa to Roma, Autostazione TiburtinabusN1508 / ...
    2. Take the bus from Roma, Autostazione Tiburtina to IserniabusRome Tiburtina
    7h 55m
    €20–58
  4. Drive 507.4 km

    1. Drive from Pisa to Iserniacar507.4 km
    4h 58m
    €78–113
  5. Fly Pisa International Airport to Naples Airport, train

    1. Fly from Pisa International Airport (PSA) to Naples Airport (NAP)planePSA - NAP
    2. Take the train from Napoli Centrale to Iserniatrain
    6h 35m
    €72–230
  6. Train via Rome

    1. Take the train from Pisa Centrale to Roma TerminitrainFb / ...
    2. Take the train from Roma Termini to IserniatrainRe
    6h 4m
    €28–81
  7. Train to Florence Peretola Airport, fly to Fiumicino International Airport, train

    1. Take the train from Pisa Centrale to Firenze S.M.N.train
    2. Fly from Florence Peretola Airport (FLR) to Fiumicino International Airport (FCO)planeFLR - FCO
    3. Take the train from Roma Termini to Iserniatrain
    7h 31m
    €88–248
  8. Train to Genoa Cristoforo Colombo Airport, fly to Naples Airport, train

    1. Take the train from Pisa Centrale to Genova P.Za Principetrain
    2. Fly from Genoa Cristoforo Colombo Airport (GOA) to Naples Airport (NAP)planeGOA - NAP
    3. Take the train from Napoli Centrale to Iserniatrain
    8h 33m
    €73–267

Pisa to Isernia by train

Calendar6Weekly Trains
Duration5h 23mAverage Duration
Ticket€48Cheapest Price
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Questions & Answers

What companies run services between Pisa, Italy and Isernia, Italy?

You can take a train from Pisa Centrale to Isernia via Roma Tiburtina in around 5h 23m. Alternatively, you can take a bus from Pisa to Isernia via Roma, Autostazione Tiburtina in around 7h 55m.

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