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How to get fromPisa to Iserniaby train (Trenitalia), bus, car, plane or train

Find Transport to Isernia

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There are 8 ways to get from Pisa to Isernia by train (Trenitalia), bus, car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Trenitalia)

    best
    1. Take the train from Pisa Centrale to Roma Tiburtinatrain train Fa
    2. Take the train from Roma Tiburtina to Iserniatrain train Re
    5h 23m
    €43–78
  2. Bus

    cheapest
    1. Take the bus from Pisa to Cassinobus bus
    2. Take the bus from Cassino Piazza Garibaldi to Iserniabus bus Cb 015
    9h 24m
    €4–6
  3. Bus via Rome

    1. Take the bus from Pisa to Roma, Autostazione Tiburtinabus bus N1508 / ...
    2. Take the bus from Roma, Autostazione Tiburtina to Iserniabus bus Rome Tiburtina
    7h 55m
    €20–41
  4. Drive 507.4 km

    1. Drive from Pisa to Iserniacar car 507.4 km
    5h 1m
    €79–113
  5. Fly Pisa International Airport to Naples Airport, train

    1. Fly from Pisa International Airport (PSA) to Naples Airport (NAP)plane plane PSA - NAP
    2. Take the train from Napoli Centrale to Iserniatrain train
    6h 35m
    €58–236
  6. Train via Rome (Trenitalia)

    1. Take the train from Pisa Centrale to Roma Terminitrain train Fb / ...
    2. Take the train from Roma Termini to Iserniatrain train Re
    6h 4m
    €28–81
  7. Train to Florence Peretola Airport, fly to Fiumicino International Airport, train

    1. Take the train from Pisa Centrale to Firenze S.M.N.train train
    2. Fly from Florence Peretola Airport (FLR) to Fiumicino International Airport (FCO)plane plane FLR - FCO
    3. Take the train from Roma Termini to Iserniatrain train
    7h 31m
    €85–240
  8. Train to Genoa Cristoforo Colombo Airport, fly to Naples Airport, train

    1. Take the train from Pisa Centrale to Genova P.Za Principetrain train
    2. Fly from Genoa Cristoforo Colombo Airport (GOA) to Naples Airport (NAP)plane plane GOA - NAP
    3. Take the train from Napoli Centrale to Iserniatrain train
    8h 33m
    €68–257

Pisa to Isernia by train (Trenitalia)

Calendar6Weekly Trains
Duration5h 23mAverage Duration
Ticket€43Cheapest Price
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Questions & Answers

What companies run services between Pisa, Italy and Isernia, Italy?

You can take a train from Pisa Centrale to Isernia via Roma Tiburtina in around 5h 23m. Alternatively, you can take a bus from Pisa to Isernia via Roma, Autostazione Tiburtina in around 7h 55m.

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