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How to get fromPisa to Iserniaby train (Trenitalia), bus, car, plane or train

Find Transport to Isernia

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There are 8 ways to get from Pisa to Isernia by train (Trenitalia), bus, car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Pisa Centrale to Roma TerminitrainFb / ...
    2. Take the train from Roma Termini to IserniatrainRe
    6h 21m
    €28–81
  2. Bus, train

    cheapest
    1. Take the bus from Pisa to Cassinobus
    2. Take the train from Cassino to IserniatrainRe
    9h 10m
    €6–9
  3. Bus

    1. Take the bus from Pisa to Roma, Autostazione TiburtinabusN1508 / ...
    2. Take the bus from Roma, Autostazione Tiburtina to IserniabusRome Tiburtina
    7h 55m
    €20–58
  4. Drive 507.4 km

    1. Drive from Pisa to Iserniacar507.4 km
    4h 58m
    €78–113
  5. Fly Pisa International Airport to Naples Airport, train

    1. Fly from Pisa International Airport (PSA) to Naples Airport (NAP)planePSA - NAP
    2. Take the train from Napoli Centrale to Iserniatrain
    6h 35m
    €72–230
  6. Train via Florence

    1. Take the train from Pisa Centrale to Firenze S.M.N.trainRe
    2. Take the train from Florence Santa Maria Novella to Roma Terminitrain
    3. Take the train from Roma Termini to IserniatrainRe
    6h 33m
    €50–95
  7. Train to Florence Peretola Airport, fly to Fiumicino International Airport, train

    1. Take the train from Pisa Centrale to Firenze S.M.N.train
    2. Fly from Florence Peretola Airport (FLR) to Fiumicino International Airport (FCO)planeFLR - FCO
    3. Take the train from Roma Termini to Iserniatrain
    7h 34m
    €88–277
  8. Train to Genoa Cristoforo Colombo Airport, fly to Naples Airport, train

    1. Take the train from Pisa Centrale to Genova Brignoletrain
    2. Fly from Genoa Cristoforo Colombo Airport (GOA) to Naples Airport (NAP)planeGOA - NAP
    3. Take the train from Napoli Centrale to Iserniatrain
    8h 25m
    €71–265

Pisa to Isernia by train

Calendar55Weekly Trains
Duration6h 21mAverage Duration
Ticket€28Cheapest Price
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Questions & Answers

What companies run services between Pisa, Italy and Isernia, Italy?

You can take a train from Pisa Centrale to Isernia via Roma Termini in around 6h 21m. Alternatively, you can take a bus from Pisa to Isernia via Roma, Autostazione Tiburtina in around 7h 55m.

Airlines
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Bus operators

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