What is the cheapest way to get from Pisa to Isernia?

The cheapest way to get from Pisa to Isernia is to bus which costs €30 - €50 and takes 9h 24m.

What is the fastest way to get from Pisa to Isernia?

The fastest way to get from Pisa to Isernia is to drive which takes 5h 1m and costs €80 - €120.

Is there a direct bus between Pisa and Isernia?

No, there is no direct bus from Pisa to Isernia. However, there are services departing from Pisa and arriving at Isernia via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 8h 40m.

Is there a direct train between Pisa and Isernia?

No, there is no direct train from Pisa to Isernia. However, there are services departing from Pisa Centrale and arriving at Isernia via Roma Termini. The journey, including transfers, takes approximately 6h 1m.

How far is it from Pisa to Isernia?

The distance between Pisa and Isernia is 516 km. The road distance is 507.4 km.

How do I travel from Pisa to Isernia without a car?

The best way to get from Pisa to Isernia without a car is to train which takes 6h 1m and costs €55 - €140.

How long does it take to get from Pisa to Isernia?

It takes approximately 6h 1m to get from Pisa to Isernia, including transfers.

Where do I catch the Pisa to Isernia bus from?

Pisa to Isernia bus services, operated by FlixBus, depart from Pisa station.

Where do I catch the Pisa to Isernia train from?

Pisa to Isernia train services, operated by Trenitalia Frecce, depart from Pisa Centrale station.

Train or bus from Pisa to Isernia?

The best way to get from Pisa to Isernia is to train which takes 6h 1m and costs €55 - €140. Alternatively, you can bus via Rome, which costs €30 - €65 and takes 8h 40m.

Where does the Pisa to Isernia bus arrive?

Pisa to Isernia bus services, operated by FlixBus, arrive at Roma, Autostazione Tiburtina station.

Where does the Pisa to Isernia train arrive?

Pisa to Isernia train services, operated by Trenitalia Frecce, arrive at Roma Termini station.

Can I drive from Pisa to Isernia?

Yes, the driving distance between Pisa to Isernia is 507 km. It takes approximately 5h 1m to drive from Pisa to Isernia.

How do I get a train ticket from Pisa to Isernia?

Book your Pisa to Isernia train tickets online with Omio.

How do I get a bus ticket from Pisa to Isernia?

Book your Pisa to Isernia bus tickets online with Omio and FlixBus.

Where can I stay near Isernia?

There are 457+ hotels available in Isernia.

Pisa to Isernia - 8 ways to travel via train, bus, car, and plane

There are 8 ways to get from Pisa to Isernia by train (Trenitalia), bus, car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Train (Trenitalia)
best
1. Take the train from Pisa Centrale to Roma Terminitrain Fb / ...
2. Take the train from Roma Termini to Iserniatrain Re
6h 1m
€58–134
Bus
cheapest
1. Take the bus from Pisa to Cassinobus
2. Take the bus from Cassino Piazza Garibaldi to Iserniabus Cb 015
9h 24m
€33–47
Bus via Rome
1. Take the bus from Pisa to Roma, Autostazione Tiburtinabus N548 / ...
2. Take the bus from Roma, Autostazione Tiburtina to Iserniabus Rome Tiburtina
8h 40m
€34–63
Drive 507.4 km
1. Drive from Pisa to Iserniacar 507.4 km
5h 1m
€81–116
Fly Pisa International Airport to Naples Airport, train
1. Fly from Pisa International Airport (PSA) to Naples Airport (NAP)plane PSA - NAP
2. Take the train from Napoli Centrale to Iserniatrain
6h 54m
€67–219
Train via Florence (Trenitalia)
1. Take the train from Pisa Centrale to Firenze S.M.N.train Re
2. Take the train from Firenze S.M.N. to Roma Terminitrain Fr
3. Take the train from Roma Termini to Iserniatrain Re
6h 48m
€60–131
Bus to Florence Peretola Airport, fly to Fiumicino International Airport, train
1. Take the bus from Pisa International Airport to Florence Airportbus
2. Fly from Florence Peretola Airport (FLR) to Fiumicino International Airport (FCO)plane FLR - FCO
3. Take the train from Roma Termini to Iserniatrain
6h 51m
€103–270
Train to Genoa Cristoforo Colombo Airport, fly to Naples Airport, train
1. Take the train from Pisa Centrale to Genova P.Za Principetrain
2. Fly from Genoa Cristoforo Colombo Airport (GOA) to Naples Airport (NAP)plane GOA - NAP
3. Take the train from Napoli Centrale to Iserniatrain
8h 44m
€82–239

Pisa to Isernia by train (Trenitalia)

35Weekly Trains

6h 1mAverage Duration

€58Cheapest Price

See schedules

Questions & Answers

Launch map view

Distance: 515.5 km
Duration: 6h 1m

What companies run services between Pisa, Italy and Isernia, Italy?

You can take a train from Pisa Centrale to Isernia via Roma Termini in around 6h 1m. Alternatively, you can take a bus from Pisa to Isernia via Roma, Autostazione Tiburtina in around 8h 40m.

Airlines

Train operators

Bus operators

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