Train Manfredonia to Isernia from €46 | Tickets & Timetables

Trip Overview

The average train between Manfredonia and Isernia takes 8h 31m and the fastest train takes 6h 20m. The train service runs several times per day from Manfredonia to Isernia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

8h 31m
Duration: 284 km
Distance: €46
Average price: 4 times a day
Frequency

Train (Trenitalia)

best

Take the train from Foggia to Casertatrain Fa / ...
Take the train from Caserta to Iserniatrain Re

5h 55m

€31–71

Manfredonia to Isernia train times

Trains run 4 times a day between Manfredonia and Isernia. The earliest departure is at 7:38 AM in the morning, and the last departure from Manfredonia is at 6:42 PM which arrives into Isernia at 9:21 AM. All services require a transfer at Foggia and take an average of 8h 31m. The schedules shown below are for the next available departures.

Departing Wednesday, May 13, 2026

7:38 AM → 2:04 PM
6h 26m • 2 changes
11:50 AM → 7:02 PM
7h 12m • 2 changes
1:48 PM → 9:40 PM
7h 52m • 2 changes
6:42 PM → 9:21 AM
Arrives next day
14h 39m • 2 changes

Departing Thursday, May 14, 2026

7:38 AM → 2:04 PM
6h 26m • 2 changes
11:50 AM → 7:02 PM
7h 12m • 2 changes
1:48 PM → 9:40 PM
7h 52m • 2 changes
6:42 PM → 9:21 AM
Arrives next day
14h 39m • 2 changes

Departing Friday, May 15, 2026

7:38 AM → 2:04 PM
6h 26m • 2 changes
11:50 AM → 7:02 PM
7h 12m • 2 changes
1:48 PM → 9:40 PM
7h 52m • 2 changes
6:42 PM → 9:21 AM
Arrives next day
14h 39m • 2 changes

Departing Saturday, May 16, 2026

7:38 AM → 2:04 PM
6h 26m • 2 changes
9:46 AM → 4:06 PM
6h 20m • 2 changes
11:50 AM → 7:02 PM
7h 12m • 2 changes
1:48 PM → 9:40 PM
7h 52m • 2 changes

Departing Sunday, May 17, 2026

7:38 AM → 2:04 PM
6h 26m • 2 changes
11:50 AM → 7:02 PM
7h 12m • 2 changes
1:48 PM → 9:32 PM
7h 44m • 2 changes
6:42 PM → 9:21 AM
Arrives next day
14h 39m • 2 changes

Departing Monday, May 18, 2026

7:38 AM → 2:04 PM
6h 26m • 2 changes
11:50 AM → 7:02 PM
7h 12m • 2 changes
1:48 PM → 9:40 PM
7h 52m • 2 changes
6:42 PM → 9:21 AM
Arrives next day
14h 39m • 2 changes

Departing Tuesday, May 19, 2026

7:38 AM → 2:04 PM
6h 26m • 2 changes
11:50 AM → 7:02 PM
7h 12m • 2 changes
1:48 PM → 9:40 PM
7h 52m • 2 changes

Frequently asked questions

Want to know about travelling from Manfredonia to Isernia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.