Rome2Rio

Roma Termini to Isernia trains

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Trip Overview

The average train between Roma Termini and Isernia takes 2h 11m and the fastest train takes 2h 5m. The train service runs several times per day from Roma Termini to Isernia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2h 11m
Duration
186 km
Distance
€26
Average price
5 times a day
Frequency

Roma Termini to Isernia train times

Trains run 5 times a day between Roma Termini and Isernia. The earliest departure is at 6:15 AM in the morning, and the last departure from Roma Termini is at 8:14 PM which arrives into Isernia at 10:23 PM. All services run direct with no transfers required, and take on average 2h 11m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

  •  → 

    train train 2h 19m • Direct

Departing Thursday, November 12, 2026

  •  → 

    train train 2h 12m • Direct
  •  → 

    train train 2h 8m • Direct
  •  → 

    train train 2h 16m • Direct
  •  → 

    train train 2h 5m • Direct
  • Show more

Departing Friday, November 13, 2026

  •  → 

    train train 2h 12m • Direct
  •  → 

    train train 2h 8m • Direct
  •  → 

    train train 2h 16m • Direct
  •  → 

    train train 2h 5m • Direct
  • Show more

Departing Saturday, November 14, 2026

  •  → 

    train train 2h 12m • Direct
  •  → 

    train train 2h 8m • Direct
  •  → 

    train train 2h 16m • Direct
  •  → 

    train train 2h 5m • Direct
  • Show more

Departing Sunday, November 15, 2026

  •  → 

    train train 2h 12m • Direct
  •  → 

    train train 2h 8m • Direct
  •  → 

    train train 2h 5m • Direct
  •  → 

    train train 2h 15m • Direct
  • Show more

Departing Monday, November 16, 2026

  •  → 

    train train 2h 12m • Direct
  •  → 

    train train 2h 8m • Direct
  •  → 

    train train 2h 16m • Direct
  •  → 

    train train 2h 5m • Direct
  • Show more

Departing Tuesday, November 17, 2026

  •  → 

    train train 2h 8m • Direct
  •  → 

    train train 2h 16m • Direct
  •  → 

    train train 2h 5m • Direct
  •  → 

    train train 2h 19m • Direct

Frequently asked questions

Want to know about travelling from Roma Termini to Isernia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Roma Termini to Isernia.ExpandLaunch map view
  • Distance: 186 km
  • Duration: 2h 11m

What companies run services between Roma Termini, Italy and Isernia, Italy?

Trenitalia operates a train from Roma Termini to Isernia 5 times a day. Tickets cost €22–30 and the journey takes 2h 8m.

Operators