The average train between Siena and Isernia takes 9h 48m and the fastest train takes 7h 43m. The train service runs several times per day from Siena to Isernia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Siena and Isernia. The earliest departure is at 10:02 AM in the morning, and the last departure from Siena is at 8:23 PM which arrives into Isernia at 8:27 AM. All services require a transfer at Chiusi-Chianciano T. and take an average of 9h 48m. The schedules shown below are for the next available departures.
Want to know about travelling from Siena to Isernia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Siena to Isernia. However, there are services departing from Siena station and arriving at Isernia station via Chiusi-Chianciano T.. The journey, including transfers, takes approximately 9h 48m.
Siena to Isernia train services, operated by Trenitalia, depart from Siena station.
Siena to Isernia train services, operated by Trenitalia, arrive at Isernia station.
Book your Siena to Isernia train tickets online with Trenitalia.
The distance between Siena and Isernia is 305.6 km. The road distance is 424 km.
You can take a train from Siena to Isernia via Chiusi-Chianciano T. and Roma Termini in around 7h 41m.
