Siena to Isernia bus times
Buses run 4 times a day between Siena and Isernia. The earliest departure is at 7:00 AM in the morning, and the last departure from Siena is at 3:45 PM which arrives into Isernia at 11:10 PM. All services require a transfer, and take on average 6h 13m. The schedules shown below are for the next available departures.
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6h 25m • 1 change
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6h 30m • 1 change
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6h • 1 change
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5h 40m • 1 change
Departing Friday, July 10, 2026
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6h 25m • 1 change
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6h 30m • 1 change
→
6h • 1 change
→
5h 40m • 1 change
