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How to get fromMemphis to Middlesboroby plane, car, or bus

Find Transport to Middlesboro

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There are 6 ways to get from Memphis to Middlesboro by plane, car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Mcghee Tyson Airport, drive

    best
    1. Fly from Memphis (MEM) to Mcghee Tyson Airport (TYS)plane plane MEM - TYS
    2. Drive from Mcghee Tyson Airport (TYS) to Middlesborocar car
    4h 23m
    $144–921

  2. Drive  431.8 mi

    cheapest
    1. Drive from Memphis to Middlesborocar car 431.8 mi
    7h 47m
    $79–114

  3. Bus, drive

    1. Take the bus from Hilton Memphis to Omni Nashville Hotelbus bus
    2. Take the bus from Nashville Bus Station to Louisville Bus Stationbus bus
    3. Take the bus from Louisville Bus Station to Cincinnati Bus Stationbus bus
    4. Take the bus from Cincinnati Bus Station to Londonbus bus
    5. Drive from London to Middlesborocar car
    16h 25m
    $228–333

  4. Fly to Tri-Cities Regional Tn/Va Airport, drive

    1. Fly from Memphis (MEM) to Tri-Cities Regional Tn/Va Airport (TRI)plane plane MEM - TRI
    2. Drive from Tri-Cities-Regional-Airport-TRI to Middlesborocar car
    6h 50m
    $93–477

  5. Fly to Asheville Regional Airport, drive

    1. Fly from Memphis (MEM) to Asheville Regional Airport (AVL)plane plane MEM - AVL
    2. Drive from Asheville-Airport-AVL to Middlesborocar car
    7h 38m
    $96–481

  6. Bus, drive via Atlanta (Greyhound)

    1. Take the bus from Memphis Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Londonbus bus
    3. Drive from London to Middlesborocar car
    18h 2m
    $110–185

Memphis (MEM) to Mcghee Tyson Airport (TYS) flights

Calendar21Weekly Planes
Duration2h 45mAverage Duration
Ticket$135Cheapest Price
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Comparing Your Travel Options

Map of how to get from Memphis to Middlesboro.ExpandLaunch map view
  • Distance: 427 mi
  • Duration: 4h 23m

What companies run services between Memphis, TN, USA and Middlesboro, KY, USA?

There is no direct connection from Memphis to Middlesboro. However, you can take the line 28 bus to Memphis International Airport, walk to Memphis (MEM) airport, fly to Mcghee Tyson Airport (TYS), then drive to Middlesboro. Alternatively, you can take a vehicle from Memphis to Middlesboro via Hilton Memphis, Omni Nashville Hotel, Peabody Station Outbound, Fulton Station Outbound, Nashville Bus Station, Louisville Bus Station, Cincinnati Bus Station, and London in around 16h 25m.

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Bus operators

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