Rome2Rio

How to get fromPhiladelphia to Middlesboroby plane, car, train or bus

Find Transport to Middlesboro

See all options

There are 11 ways to get from Philadelphia to Middlesboro by plane, car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Philadelphia International Airport to Mcghee Tyson Airport, drive

    best
    1. Fly from Philadelphia International Airport (PHL) to Mcghee Tyson Airport (TYS)plane plane PHL - TYS
    2. Drive from Mcghee Tyson Airport (TYS) to Middlesborocar car
    5h 12m
    $148–811

  2. Fly Philadelphia International Airport to Blue Grass Airport, drive

    cheapest
    1. Fly from Philadelphia International Airport (PHL) to Blue Grass Airport (LEX)plane plane PHL - LEX
    2. Drive from Lexington-Airport-LEX to Middlesborocar car
    6h 19m
    $87–416

  3. Train, bus, drive

    1. Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the bus from New York to Knoxvillebus bus Nyc
    3. Drive from Knoxville to Middlesborocar car
    16h 22m
    $125–760

  4. Drive 596.1 mi

    1. Drive from Philadelphia to Middlesborocar car 596.1 mi
    10h 59m
    $109–158

  5. Fly Philadelphia International Airport to Asheville Regional Airport, drive

    1. Fly from Philadelphia International Airport (PHL) to Asheville Regional Airport (AVL)plane plane PHL - AVL
    2. Drive from Asheville-Airport-AVL to Middlesborocar car
    6h 27m
    $88–418

  6. Train to Baltimore-Washington International Airport, fly to Mcghee Tyson Airport, drive

    1. Take the train from 30th Street Station to BWI Thurgood Marshalltrain train
    2. Fly from Baltimore-Washington International Airport (BWI) to Mcghee Tyson Airport (TYS)plane plane BWI - TYS
    3. Drive from Mcghee Tyson Airport (TYS) to Middlesborocar car
    6h 1m
    $229–1,118

  7. Fly Philadelphia International Airport to Greenville–Spartanburg International Airport, drive

    1. Fly from Philadelphia International Airport (PHL) to Greenville–Spartanburg International Airport (GSP)plane plane PHL - GSP
    2. Drive from Greenville–Spartanburg International Airport (GSP) to Middlesborocar car
    7h 31m
    $123–577

  8. Train to Laguardia Airport, fly to Mcghee Tyson Airport, drive

    1. Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Fly from Laguardia Airport (LGA) to Mcghee Tyson Airport (TYS)plane plane LGA - TYS
    3. Drive from Mcghee Tyson Airport (TYS) to Middlesborocar car
    7h 52m
    $172–1,432

  9. Train, bus, drive via Farragut

    1. Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the bus from New York City to Knoxvillebus bus Ny
    3. Drive from Knoxville to Middlesborocar car
    16h 26m
    $108–717

  10. Bus, drive

    1. Take the bus from Philadelphia, PA to New York, NYbus bus
    2. Take the bus from New York City to Knoxvillebus bus Ny
    3. Drive from Knoxville to Middlesborocar car
    17h 7m
    $114–188

  11. Bus, drive via Dayton (Greyhound)

    1. Take the bus from Philadelphia to Dayton Trotwood Bus Stationbus bus
    2. Take the bus from Dayton Trotwood Bus Station to Londonbus bus
    3. Drive from London to Middlesborocar car
    20h 26m
    $132–279

Philadelphia International Airport (PHL) to Mcghee Tyson Airport (TYS) flights

Calendar68Weekly Planes
Duration3h 44mAverage Duration
Ticket$135Cheapest Price
See schedules

Questions & Answers

What companies run services between Philadelphia, PA, USA and Middlesboro, KY, USA?

There is no direct connection from Philadelphia to Middlesboro. However, you can take the train to Airport Terminal A, walk to Philadelphia International Airport (PHL) airport, fly to Mcghee Tyson Airport (TYS), then drive to Middlesboro. Alternatively, you can take a train from 30th Street Station to Middlesboro via Ny Moynihan Train Hall At Penn Station, 34 St-Herald Sq, East Broadway, New York, and Knoxville in around 16h 22m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Trips from Philadelphia

Trips to Middlesboro

Popular routes