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How to get fromPhiladelphia to Middlesboroby plane, car, bus, or train

Find Transport to Middlesboro

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There are 10 ways to get from Philadelphia to Middlesboro by plane, car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Philadelphia International Airport to Mcghee Tyson Airport, drive

    best
    1. Fly from Philadelphia International Airport (PHL) to Mcghee Tyson Airport (TYS)plane plane PHL - TYS
    2. Drive from Mcghee Tyson Airport (TYS) to Middlesborocar car
    5h 10m
    $186–1,024

  2. Fly Philadelphia International Airport to Blue Grass Airport, drive

    cheapest
    1. Fly from Philadelphia International Airport (PHL) to Blue Grass Airport (LEX)plane plane PHL - LEX
    2. Drive from Lexington-Airport-LEX to Middlesborocar car
    6h 6m
    $101–499

  3. Bus, drive

    1. Take the bus from Philadelphia Bus Station to New York City Chinatownbus bus
    2. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    3. Drive from Knoxville, TN to Middlesborocar car
    17h 3m
    $128–160

  4. Drive  596.4 mi

    1. Drive from Philadelphia to Middlesborocar car 596.4 mi
    10h 59m
    $109–158

  5. Train to Baltimore-Washington International Airport, fly to Mcghee Tyson Airport, drive

    1. Take the train from 30th Street Station to BWI Thurgood Marshalltrain train
    2. Fly from Baltimore-Washington International Airport (BWI) to Mcghee Tyson Airport (TYS)plane plane BWI - TYS
    3. Drive from Mcghee Tyson Airport (TYS) to Middlesborocar car
    5h 52m
    $177–1,528

  6. Fly Philadelphia International Airport to Asheville Regional Airport, drive

    1. Fly from Philadelphia International Airport (PHL) to Asheville Regional Airport (AVL)plane plane PHL - AVL
    2. Drive from Asheville-Airport-AVL to Middlesborocar car
    6h 35m
    $103–494

  7. Fly Philadelphia International Airport to Greenville–Spartanburg International Airport, drive

    1. Fly from Philadelphia International Airport (PHL) to Greenville–Spartanburg International Airport (GSP)plane plane PHL - GSP
    2. Drive from Greenville–Spartanburg International Airport (GSP) to Middlesborocar car
    7h 30m
    $148–759

  8. Train to Laguardia Airport, fly to Mcghee Tyson Airport, drive

    1. Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Fly from Laguardia Airport (LGA) to Mcghee Tyson Airport (TYS)plane plane LGA - TYS
    3. Drive from Mcghee Tyson Airport (TYS) to Middlesborocar car
    7h 43m
    $232–1,733

  9. Bus, drive via Dayton

    1. Take the bus from Philadelphia Bus Station to Dayton Trotwood Bus Stationbus bus
    2. Take the bus from Dayton Trotwood Bus Station to Londonbus bus
    3. Drive from London to Middlesborocar car
    20h 31m
    $124–207

  10. Bus, drive via Reading

    1. Take the bus from Philadelphia Bus Station to Cincinnatibus bus
    2. Take the bus from Cincinnati Bus Station to Londonbus bus
    3. Drive from London to Middlesborocar car
    20h 31m
    $131–230

Philadelphia International Airport (PHL) to Mcghee Tyson Airport (TYS) flights

Calendar94Weekly Planes
Duration3h 33mAverage Duration
Ticket$174Cheapest Price
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Comparing Your Travel Options

Map of how to get from Philadelphia to Middlesboro.ExpandLaunch map view
  • Distance: 635.5 mi
  • Duration: 5h 10m

What companies run services between Philadelphia, PA, USA and Middlesboro, KY, USA?

There is no direct connection from Philadelphia to Middlesboro. However, you can take the train to Airport Terminal A, walk to Philadelphia International Airport (PHL) airport, fly to Mcghee Tyson Airport (TYS), then drive to Middlesboro. Alternatively, you can take a bus from Philadelphia Bus Station to Middlesboro via New York, NY and Knoxville, TN in around 17h 3m.

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