There are 10 ways to get from Philadelphia to Middlesboro by plane, car, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Philadelphia International Airport to Mcghee Tyson Airport, drive
best- Fly from Philadelphia International Airport (PHL) to Mcghee Tyson Airport (TYS)PHL - TYS
- Drive from Mcghee Tyson Airport (TYS) to Middlesboro
5h 12m$328–516Fly Philadelphia International Airport to Asheville Regional Airport, drive
cheapest- Fly from Philadelphia International Airport (PHL) to Asheville Regional Airport (AVL)PHL - AVL
- Drive from Asheville-Airport-AVL to Middlesboro
6h 29m$91–411Bus, drive
- Take the bus from Philadelphia to New York City Chinatown
- Take the bus from New York City to KnoxvilleNy
- Drive from Knoxville to Middlesboro
17h 2m$108–152Train, bus, drive
- Take the train from 30th Street Station to Indianapolis
- Take the bus from Indianapolis Union Station to Lexington Bus Stop
- Take the bus from Lexington Bus Stop to London
- Drive from London to Middlesboro
29h 46m$169–671Drive 594.1 mi
- Drive from Philadelphia to Middlesboro594.1 mi
10h 59m$109–157Train to Newark Liberty International Airport, fly to Mcghee Tyson Airport, drive
- Take the train from 30th Street Station to Newark Liberty International Airport
- Fly from Newark Liberty International Airport (EWR) to Mcghee Tyson Airport (TYS)EWR - TYS
- Drive from Mcghee Tyson Airport (TYS) to Middlesboro
5h 54m$283–679Train to Baltimore-Washington International Airport, fly to Mcghee Tyson Airport, drive
- Take the train from 30th Street Station to BWI Thurgood Marshall
- Fly from Baltimore-Washington International Airport (BWI) to Mcghee Tyson Airport (TYS)BWI - TYS
- Drive from Mcghee Tyson Airport (TYS) to Middlesboro
6h 1m$228–1,328Train to Laguardia Airport, fly to Mcghee Tyson Airport, drive
- Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Station
- Fly from Laguardia Airport (LGA) to Mcghee Tyson Airport (TYS)LGA - TYS
- Drive from Mcghee Tyson Airport (TYS) to Middlesboro
7h 36m$352–1,082Fly Philadelphia International Airport to Greenville–Spartanburg International Airport, drive
- Fly from Philadelphia International Airport (PHL) to Greenville–Spartanburg International Airport (GSP)PHL - GSP
- Drive from Greenville–Spartanburg International Airport (GSP) to Middlesboro
7h 29m$235–531Bus, train, drive
- Take the bus from Market St At 13Th St to Wallenberg Ave Across From Terminal409
- Take the train from Trenton Transit Center to New York Penn StationNec
- Take the bus from New York to KnoxvilleNyc
- Drive from Knoxville to Middlesboro
19h 15m$121–207
Philadelphia International Airport (PHL) to Mcghee Tyson Airport (TYS) flights
Questions & Answers
The cheapest way to get from Philadelphia to Middlesboro is to bus and drive which costs $100 - $160 and takes 17h 2m.
The fastest way to get from Philadelphia to Middlesboro is to fly and drive which takes 5h 12m and costs $320 - $550.
The distance between Philadelphia and Middlesboro is 639 miles. The road distance is 597.6 miles.
It takes approximately 5h 12m to get from Philadelphia to Middlesboro, including transfers.
Yes, the driving distance between Philadelphia to Middlesboro is 598 miles. It takes approximately 10h 59m to drive from Philadelphia to Middlesboro.
There are 25+ hotels available in Middlesboro.
What companies run services between Philadelphia, PA, USA and Middlesboro, KY, USA?
There is no direct connection from Philadelphia to Middlesboro. However, you can take the train to Airport Terminal A, walk to Philadelphia International Airport (PHL) airport, fly to Mcghee Tyson Airport (TYS), then drive to Middlesboro. Alternatively, you can take a bus from Philadelphia to Middlesboro via New York City and Knoxville in around 17h 2m.
- Website
- aa.com
Flights from Philadelphia International Airport to Mcghee Tyson Airport
- Ave. Duration
- 2h 11m
- When
- Every day
- Estimated price
- $120–700
Flights from Philadelphia International Airport to Mcghee Tyson Airport via Charlotte
- Ave. Duration
- 4h 13m
- When
- Every day
- Estimated price
- $120–700
Flights from Newark Liberty International Airport to Mcghee Tyson Airport via Charlotte
- Ave. Duration
- 4h 32m
- When
- Every day
- Estimated price
- $110–600
Flights from Baltimore-Washington International Airport to Mcghee Tyson Airport via Charlotte
- Ave. Duration
- 4h 3m
- When
- Every day
- Estimated price
- $100–600
Flights from Philadelphia International Airport to Asheville Regional Airport
- Ave. Duration
- 2h 5m
- When
- Every day
- Estimated price
- $65–380
Flights from Philadelphia International Airport to Asheville Regional Airport via Charlotte
- Ave. Duration
- 4h 6m
- When
- Every day
- Estimated price
- $65–380
Flights from Laguardia Airport to Mcghee Tyson Airport
- Ave. Duration
- 2h 15m
- When
- Every day
- Estimated price
- $120–650
Flights from Laguardia Airport to Mcghee Tyson Airport via Charlotte
- Ave. Duration
- 4h 29m
- When
- Every day
- Estimated price
- $120–700
Flights from Philadelphia International Airport to Greenville–Spartanburg International Airport
- Ave. Duration
- 2h 4m
- When
- Every day
- Estimated price
- $95–550
Flights from Philadelphia International Airport to Greenville–Spartanburg International Airport via Charlotte
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- $95–550
- Website
- delta.com
Flights from Philadelphia International Airport to Mcghee Tyson Airport via Atlanta
- Ave. Duration
- 4h 48m
- When
- Every day
- Estimated price
- $140–750
Flights from Newark Liberty International Airport to Mcghee Tyson Airport via Atlanta
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- $120–650
Flights from Baltimore-Washington International Airport to Mcghee Tyson Airport via Atlanta
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $120–700
Flights from Philadelphia International Airport to Asheville Regional Airport via Atlanta
- Ave. Duration
- 4h 50m
- When
- Every day
- Estimated price
- $85–440
Flights from Philadelphia International Airport to Asheville Regional Airport via Boston
- Ave. Duration
- 5h 8m
- When
- Saturday and Sunday
- Estimated price
- $100–490
Flights from Laguardia Airport to Mcghee Tyson Airport
- Ave. Duration
- 2h 21m
- When
- Every day
- Estimated price
- $120–650
Flights from Laguardia Airport to Mcghee Tyson Airport via Atlanta
- Ave. Duration
- 4h 51m
- When
- Every day
- Estimated price
- $140–750
Flights from Philadelphia International Airport to Greenville–Spartanburg International Airport via Atlanta
- Ave. Duration
- 4h 49m
- When
- Every day
- Estimated price
- $120–650
- Website
- united.com
Flights from Philadelphia International Airport to Mcghee Tyson Airport via Washington Dulles
- Ave. Duration
- 4h 42m
- When
- Every day
- Estimated price
- $120–700
Flights from Newark Liberty International Airport to Mcghee Tyson Airport via Washington Dulles
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- $100–550
Flights from Laguardia Airport to Mcghee Tyson Airport via Washington Dulles
- Ave. Duration
- 4h 36m
- When
- Every day
- Estimated price
- $120–650
Flights from Philadelphia International Airport to Greenville–Spartanburg International Airport via Washington Dulles
- Ave. Duration
- 4h 26m
- When
- Every day
- Estimated price
- $95–550
- Website
- allegiantair.com
Flights from Philadelphia International Airport to Mcghee Tyson Airport
- Ave. Duration
- 2h 3m
- When
- Thursday
- Estimated price
- $120–700
Flights from Newark Liberty International Airport to Mcghee Tyson Airport
- Ave. Duration
- 2h 2m
- When
- Every day
- Estimated price
- $100–550
- Website
- southwest.com
Flights from Baltimore-Washington International Airport to Mcghee Tyson Airport
- Ave. Duration
- 1h 45m
- When
- Monday, Thursday, Friday, and Saturday
- Estimated price
- $100–600
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from 30th Street Station to Indianapolis
- Ave. Duration
- 21h
- Frequency
- 3 times a week
- Estimated price
- $100–550
- Website
- https://www.amtrak.com/home.html
Train from 30th Street Station to Newark Liberty International Airport
- Ave. Duration
- 1h 2m
- Frequency
- Twice a week
- Estimated price
- $10–65
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $18–29
- Coach Seat short notice purchase
- $10–65
- Business - advance purchase
- $13–95
- Business Class
- $23–180
Train from 30th Street Station to BWI Thurgood Marshall
- Ave. Duration
- 1h 27m
- Frequency
- Twice daily
- Estimated price
- $16–240
- Website
- https://www.amtrak.com/home.html
Train from 30th Street Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 1h 24m
- Frequency
- Hourly
- Estimated price
- $25–320
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Amtrak Northeast Regional
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from 30th Street Station to Newark Liberty International Airport
- Ave. Duration
- 57 min
- Frequency
- Every 2 hours
- Estimated price
- $10–220
- Website
- https://www.amtrak.com/home.html
- Schedules at
- https://www.amtrak.com/northeast-regional-train
- Coach
- $10–220
- Business Class
- $55–260
Train from 30th Street Station to BWI Thurgood Marshall
- Ave. Duration
- 1h 25m
- Frequency
- Hourly
- Estimated price
- $14–240
- Website
- https://www.amtrak.com/home.html
- Schedules at
- https://www.amtrak.com/northeast-regional-train
- Coach
- $14–240
- Business Class
- $60–280
Train from 30th Street Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 1h 26m
- Frequency
- Hourly
- Estimated price
- $12–230
- Website
- https://www.amtrak.com/home.html
- Schedules at
- https://www.amtrak.com/northeast-regional-train
- Coach
- $12–230
- Business Class
- $60–270
Rome2Rio's guide to Amtrak Acela
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from 30th Street Station to BWI Thurgood Marshall
- Ave. Duration
- 1h 24m
- Frequency
- 5 times a day
- Estimated price
- $24–650
- Schedules at
- https://www.amtrak.com/acela-train
- Website
- https://www.amtrak.com/home.html
- Business Class
- $24–460
- First Class
- $140–650
Train from 30th Street Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 1h 20m
- Frequency
- Every 2 hours
- Estimated price
- $20–600
- Schedules at
- https://www.amtrak.com/acela-train
- Website
- https://www.amtrak.com/home.html
- Business Class
- $20–460
- First Class
- $130–600
- Phone
- +1 973-275-5555
- Website
- njtransit.com
Train from Trenton Transit Center to New York Penn Station
- Ave. Duration
- 1h 33m
- Frequency
- Every 30 minutes
- Estimated price
- $2–23
- Website
- https://www.njtransit.com/
- Schedules at
- https://www.njtransit.com/bus-to
- Adult
- $2–23
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Philadelphia to New York City Chinatown
- Ave. Duration
- 2h 30m
- Frequency
- Twice daily
- Estimated price
- $15–35
- Schedules at
- flixbus.com
- Phone
- +1 615-939-8887
- jpan12692@gmail.com
- Website
- nytnbus.com
Bus from New York City to Knoxville
- Ave. Duration
- 12h
- Frequency
- 3 times a week
- Estimated price
- $80–100
- Schedules at
- nytnbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Indianapolis Union Station to Lexington Bus Stop
- Ave. Duration
- 3h 50m
- Frequency
- Once daily
- Estimated price
- $30–80
- Website
- https://www.greyhound.com/
Bus from Lexington Bus Stop to London
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Estimated price
- $27–60
- Website
- https://www.greyhound.com/
- Phone
- +1 973-275-5555
- Website
- njtransit.com
Bus from Market St At 13Th St to Wallenberg Ave Across From Terminal
- Ave. Duration
- 2h 31m
- Frequency
- Hourly
- Estimated price
- $6–21
- Website
- https://www.njtransit.com/
- Schedules at
- https://www.njtransit.com/bus-to
- Adults
- $6–21
- Phone
- +1 646-630-7186
- help@wandacoach.com
- Website
- wandacoach.com
Bus from New York to Knoxville
- Ave. Duration
- 11h 45m
- Frequency
- 3 times a week
- Estimated price
- $95–140
- Website
- https://www.wandacoach.com
- Book at
- https://www.gotobus.com/wanda-travel/
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