There are 3 ways to get from Kentucky to Middlesboro by bus or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, drive
best- Take the bus from Louisville, KY to Indianapolis Union Stationbus
- Take the bus from Indianapolis to Cincinnatibus
- Take the bus from Cincinnati Bus Station to Londonbus
- Drive from London to Middlesborocar
12h 6m$72–153Drive 189.4 mi
cheapest- Drive from Louisville to Middlesborocar 189.4 mi
4h 13m$35–50Bus, drive via Speedway
- Take the bus from El Mercadito Grocery - Clarksville, IN to Indianapolisbus
- Take the bus from Indianapolis to Cincinnatibus
- Take the bus from Cincinnati Bus Station to Londonbus
- Drive from London to Middlesborocar
14h 26m$77–159
Comparing Your Travel Options
The cheapest way to get from Kentucky to Middlesboro is to drive which costs $30 - $50 and takes 4h 13m.
The fastest way to get from Kentucky to Middlesboro is to drive which takes 4h 13m and costs $30 - $50.
The distance between Kentucky and Middlesboro is 477 miles. The road distance is 190.5 miles.
It takes approximately 12h 6m to get from Kentucky to Middlesboro, including transfers.
Yes, the driving distance between Kentucky to Middlesboro is 191 miles. It takes approximately 4h 13m to drive from Kentucky to Middlesboro.
There are 20+ hotels available in Middlesboro.
What companies run services between Kentucky, USA and Middlesboro, KY, USA?
There is no direct connection from Kentucky to Middlesboro. However, you can take the bus to Indianapolis Union Station, take the bus to Cincinnati, walk to Cincinnati Bus Station, take the bus to London, then drive to Middlesboro. Alternatively, you can drive from Louisville to Middlesboro in around 4h 13m.
Rome2Rio's guide to Amtrak Thruway
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Louisville, KY to Indianapolis Union Station
- Ave. Duration
- 2h 20m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Amtrak
- Adult
- $22–45
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- Barons Bus
Bus from Indianapolis to Cincinnati
- Ave. Duration
- 2h 55m
- Frequency
- Twice daily
- Estimated price
- $13–50
- Website
- Barons Bus
Bus from Indianapolis to Cincinnati
- Ave. Duration
- 2h 55m
- Frequency
- Twice daily
- Estimated price
- $13–50
- Website
- Barons Bus
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Cincinnati Bus Station to London
- Ave. Duration
- 3h 30m
- Frequency
- Once daily
- Estimated price
- $27–45
- Website
- Greyhound
Bus from Cincinnati Bus Station to London
- Ave. Duration
- 3h 30m
- Frequency
- Once daily
- Estimated price
- $27–45
- Website
- Greyhound
- Phone
- +1 888 358 6762
- info@tornadobus.com
- Website
- Tornado Bus Company
Bus from El Mercadito Grocery - Clarksville, IN to Indianapolis
- Ave. Duration
- 2h 10m
- Frequency
- 3 times a week
- Estimated price
- $24–45
- Schedules at
- Tornado Bus Company
- Adult
- $24–45
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