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How to get fromIndianapolis to Middlesboroby bus, car or plane

Find Transport to Middlesboro

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There are 5 ways to get from Indianapolis to Middlesboro by bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, drive (Greyhound)

    best
    1. Take the bus from Indianapolis Union Station to Lexington Bus Stopbus bus
    2. Take the bus from Lexington Bus Stop to Londonbus bus
    3. Drive from London to Middlesborocar car
    7h 46m
    $76–148

  2. Drive 301.9 mi

    cheapest
    1. Drive from Indianapolis to Middlesborocar car 301.9 mi
    5h 40m
    $56–80

  3. Fly to Mcghee Tyson Airport, drive

    1. Fly from Indianapolis (IND) to Mcghee Tyson Airport (TYS)plane plane IND - TYS
    2. Drive from Mcghee Tyson Airport (TYS) to Middlesborocar car
    7h 4m
    $115–672

  4. Bus, drive via Reading

    1. Take the bus from Indianapolis, IN to Greyhound Station Cincinnatibus bus
    2. Take the bus from Cincinnati Bus Station to Londonbus bus
    3. Drive from London to Middlesborocar car
    8h 41m
    $58–133

  5. Fly to Tri-Cities Regional Tn/Va Airport, drive

    1. Fly from Indianapolis (IND) to Tri-Cities Regional Tn/Va Airport (TRI)plane plane IND - TRI
    2. Drive from Tri-Cities-Regional-Airport-TRI to Middlesborocar car
    7h 43m
    $114–578

Indianapolis (IND) to Mcghee Tyson Airport (TYS) flights

Calendar108Weekly Planes
Duration4h 28mAverage Duration
Ticket$104Cheapest Price
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Questions & Answers

What companies run services between Indianapolis, IN, USA and Middlesboro, KY, USA?

There is no direct connection from Indianapolis to Middlesboro. However, you can take the bus to Lexington Bus Stop, take the bus to London, then drive to Middlesboro. Alternatively, you can drive from Indianapolis to Middlesboro in around 5h 40m.

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Need to know: Greyhound

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