There are 7 ways to get from Boston to Middlesboro by plane, car, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Mcghee Tyson Airport, drive
best- Fly from Boston Logan Airport (BOS) to Mcghee Tyson Airport (TYS)BOS - TYS
- Drive from Mcghee Tyson Airport (TYS) to Middlesboro
4h 13m$150–704Fly to Asheville Regional Airport, drive
cheapest- Fly from Boston Logan Airport (BOS) to Asheville Regional Airport (AVL)BOS - AVL
- Drive from Asheville-Airport-AVL to Middlesboro
5h 21m$101–427Bus, drive
- Take the bus from Boston, MA - 177 Huntington Ave to Times Square – 37th St.
- Take the bus from New York to KnoxvilleNyc
- Drive from Knoxville to Middlesboro
18h 43m$130–209Train, bus, drive via Toledo
- Take the train from Boston to Toledo
- Take the bus from Toledo Bus Stop to London
- Drive from London to Middlesboro
28h 34m$180–829Drive 895.7 mi
- Drive from Boston to Middlesboro895.7 mi
16h 2m$164–237Train, bus, drive
- Take the train from Boston to Ny Moynihan Train Hall At Penn Station
- Take the bus from New York City to KnoxvilleNy
- Drive from Knoxville to Middlesboro
19h 2m$127–835Bus, drive via Farragut
- Take the bus from Boston to New York City Chinatown
- Take the bus from New York City to KnoxvilleNy
- Drive from Knoxville to Middlesboro
19h 37m$124–179
Boston Logan Airport (BOS) to Mcghee Tyson Airport (TYS) flights
Questions & Answers
The cheapest way to get from Boston to Middlesboro is to bus and drive via Farragut which costs $120 - $180 and takes 19h 37m.
The fastest way to get from Boston to Middlesboro is to fly and drive which takes 4h 13m and costs $150 - $750.
The distance between Boston and Middlesboro is 908 miles. The road distance is 900.9 miles.
It takes approximately 4h 13m to get from Boston to Middlesboro, including transfers.
Yes, the driving distance between Boston to Middlesboro is 901 miles. It takes approximately 16h 2m to drive from Boston to Middlesboro.
There are 25+ hotels available in Middlesboro.
What companies run services between Boston, MA, USA and Middlesboro, KY, USA?
There is no direct connection from Boston to Middlesboro. However, you can fly to Mcghee Tyson Airport (TYS) then drive to Middlesboro. Alternatively, you can take a bus from Boston, MA - 177 Huntington Ave to Middlesboro via Times Square – 37th St., 34 St-Herald Sq, East Broadway, New York, and Knoxville in around 18h 43m.
- Website
- aa.com
Flights from Boston Logan Airport to Mcghee Tyson Airport via Charlotte
- Ave. Duration
- 4h 56m
- When
- Every day
- Estimated price
- $140–750
Flights from Boston Logan Airport to Mcghee Tyson Airport via Philadelphia
- Ave. Duration
- 4h 51m
- When
- Every day
- Estimated price
- $130–700
Flights from Boston Logan Airport to Mcghee Tyson Airport via Reagan Washington
- Ave. Duration
- 5h 2m
- When
- Every day
- Estimated price
- $130–700
Flights from Boston Logan Airport to Asheville Regional Airport via Reagan Washington
- Ave. Duration
- 5h 8m
- When
- Every day
- Estimated price
- $75–390
Flights from Boston Logan Airport to Asheville Regional Airport via Charlotte
- Ave. Duration
- 5h 2m
- When
- Every day
- Estimated price
- $75–400
- Website
- delta.com
Flights from Boston Logan Airport to Mcghee Tyson Airport via New York La Guardia
- Ave. Duration
- 5h 58m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $130–700
Flights from Boston Logan Airport to Asheville Regional Airport
- Ave. Duration
- 2h 43m
- When
- Saturday and Sunday
- Estimated price
- $75–390
Flights from Boston Logan Airport to Asheville Regional Airport via Atlanta
- Ave. Duration
- 5h 22m
- When
- Every day
- Estimated price
- $95–450
- Website
- allegiantair.com
Flights from Boston Logan Airport to Mcghee Tyson Airport
- Ave. Duration
- 2h 31m
- When
- Tuesday, Thursday, Saturday, and Sunday
- Estimated price
- $130–700
Flights from Boston Logan Airport to Asheville Regional Airport
- Ave. Duration
- 2h 27m
- When
- Monday, Wednesday, and Saturday
- Estimated price
- $75–390
- Website
- united.com
Flights from Boston Logan Airport to Mcghee Tyson Airport via Washington Dulles
- Ave. Duration
- 5h 30m
- When
- Every day
- Estimated price
- $130–700
- Website
- southwest.com
Flights from Boston Logan Airport to Mcghee Tyson Airport via Baltimore
- Ave. Duration
- 4h 30m
- When
- Monday and Friday
- Estimated price
- $130–700
- Website
- jetblue.com
Flights from Boston Logan Airport to Asheville Regional Airport
- Ave. Duration
- 2h 24m
- When
- Saturday and Sunday
- Estimated price
- $75–390
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Boston to Toledo
- Ave. Duration
- 17h 23m
- Frequency
- Once daily
- Estimated price
- $120–750
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Amtrak Northeast Regional
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Boston to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 4h 2m
- Frequency
- Every 3 hours
- Estimated price
- $30–300
- Website
- https://www.amtrak.com/home.html
- Schedules at
- https://www.amtrak.com/northeast-regional-train
- Coach
- $30–300
- Business Class
- $95–360
Rome2Rio's guide to Amtrak Acela
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Boston to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 3h 41m
- Frequency
- Every 4 hours
- Estimated price
- $50–750
- Schedules at
- https://www.amtrak.com/acela-train
- Website
- https://www.amtrak.com/home.html
- Business Class
- $50–490
- First Class
- $200–750
- Phone
- +1 617-681-0820
- support@coachrun.com
- Website
- coachrun.com
Bus from Boston, MA - 177 Huntington Ave to Times Square – 37th St.
- Ave. Duration
- 3h 50m
- Frequency
- Twice daily
- Estimated price
- $17–45
- Website
- https://www.coachrun.com
- Phone
- +1 646-630-7186
- help@wandacoach.com
- Website
- wandacoach.com
Bus from New York to Knoxville
- Ave. Duration
- 11h 45m
- Frequency
- 3 times a week
- Estimated price
- $95–140
- Website
- https://www.wandacoach.com
- Book at
- https://www.gotobus.com/wanda-travel/
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Toledo Bus Stop to London
- Ave. Duration
- 8h 50m
- Frequency
- Once daily
- Estimated price
- $50–100
- Website
- https://www.greyhound.com/
- Phone
- +1 615-939-8887
- jpan12692@gmail.com
- Website
- nytnbus.com
Bus from New York City to Knoxville
- Ave. Duration
- 12h
- Frequency
- 3 times a week
- Estimated price
- $80–100
- Schedules at
- nytnbus.com
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Boston to New York City Chinatown
- Ave. Duration
- 5h
- Frequency
- Every 4 hours
- Estimated price
- $30–65
- Schedules at
- flixbus.com
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