The average train between Modena and Isernia takes 7h 48m and the fastest train takes 5h 25m. The train service runs several times per day from Modena to Isernia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Modena and Isernia. The earliest departure is at 9:16 AM in the morning, and the last departure from Modena is at 8:16 PM which arrives into Isernia at 8:27 AM. All services require a transfer at Bologna centrale and take an average of 7h 48m. The schedules shown below are for the next available departures.


6h 7m • 2 changes


7h 14m • 2 changes


6h 28m • 2 changes
Arrives next day


12h 11m • 2 changes


7h 14m • 2 changes


6h 29m • 2 changes


5h 25m • 2 changes
Arrives next day


12h 11m • 2 changes


6h 7m • 2 changes


7h 14m • 2 changes


6h 28m • 2 changes
Arrives next day


12h 11m • 2 changes


6h 7m • 2 changes


7h 14m • 2 changes


6h 28m • 2 changes
Arrives next day


12h 11m • 2 changes
Want to know about travelling from Modena to Isernia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Modena to Isernia. However, there are services departing from Modena station and arriving at Isernia station via Roma Termini. The journey, including transfers, takes approximately 7h 48m.
Modena to Isernia train services, operated by Trenitalia Frecce, depart from Bologna centrale station.
Modena to Isernia train services, operated by Trenitalia Frecce, arrive at Isernia station.
Book your Modena to Isernia train tickets online with Trenitalia Frecce, ItaloTreno and 2 other operators.
The distance between Modena and Isernia is 432.7 km. The road distance is 572 km.
You can take a train from Modena to Isernia via Bologna centrale and Roma Termini in around 6h 5m.