The average train between Messina and Isernia takes 15h 19m and the fastest train takes 8h 47m. The train runs, on average, 4 times per week from Messina to Isernia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a week between Messina and Isernia. The earliest departure is at 10:15 AM in the morning, and the last departure from Messina is at 2:20 PM which arrives into Isernia at 2:04 PM. All services require a transfer, and take on average 15h 19m. The schedules shown below are for the next available departures.
Want to know about travelling from Messina to Isernia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Messina to Isernia. However, there are services departing from Messina station and arriving at Isernia station via Caserta. The journey, including transfers, takes approximately 15h 19m.
Messina to Isernia train services, operated by Trenitalia Intercity, depart from Messina Centrale station.
Messina to Isernia train services, operated by Trenitalia Intercity, arrive at Isernia station.
Book your Messina to Isernia train tickets online with Trenitalia Intercity and Trenitalia.
The distance between Messina and Isernia is 394.7 km. The road distance is 556 km.
You can take a train from Messina Centrale to Isernia via Caserta in around 8h 56m.