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The train between Milan and Isernia takes 6h 14m. There is at least one train per day from Milan to Isernia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run once daily between Milan and Isernia. The service departs Milan at 10:26 AM in the morning, which arrives into Isernia at 16:40:00. All services require a transfer, and take on average 6h 14m. The schedules shown below are for the next available departures.
Want to know about travelling from Milan to Isernia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Milan to Isernia. However, there are services departing from Milan Rogoredo station and arriving at Isernia station via Roma Termini station. The journey, including transfers, takes approximately 6h 14m.
Milan to Isernia train services, operated by ItaloTreno, depart from Milan Rogoredo station.
Milan to Isernia train services, operated by Trenitalia, arrive at Isernia station.
Book your Milan to Isernia train tickets online with Omio.
The distance between Milan and Isernia is 591.7 km. The road distance is 726 km.
You can take a train from Milan Rogoredo to Isernia via Roma Termini in around 6h 7m.
