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How to get fromMessina to Iserniaby ferry, train, bus, car, plane, or train (Trenitalia)

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There are 9 ways to get from Messina to Isernia by ferry, train, bus, car, plane, or train (Trenitalia)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Ferry, train

    best
    1. Take the ferry from Messina Marittima to Villa S.Giovanniferry ferry M1 / ...
    2. Take the train from Villa S.Giovanni to Napoli Afragolatrain train Fr
    3. Take the train from Napoli Afragola to Iserniatrain train Re
    8h 4m

  2. Bus via Caserta

    cheapest
    1. Take the bus from Messina Centrale Station to Caserta pzza Garibaldibus bus Autoservizi Salemi S202
    2. Take the bus from Caserta Terminal Bus to Iserniabus bus 433
    8h 49m
    €27–56

  3. Ferry, drive

    1. Take the ferry from Messina Marittima to Villa San Giovanniferry ferry
    2. Drive from Villa San Giovanni to Iserniacar car
    6h 5m
    €92–142

  4. Train to Catania–Fontanarossa Airport, fly to Naples Airport, train

    1. Take the train from Messina Centrale to Catania Centraletrain train
    2. Fly from Catania–Fontanarossa Airport (CTA) to Naples Airport (NAP)plane plane CTA - NAP
    3. Take the train from Caserta to Iserniatrain train
    8h 21m
    €49–210

  5. Train (Trenitalia)

    1. Take the train from Messina Centrale to Napoli Centraletrain train Ic
    2. Take the train from Napoli Centrale to Iserniatrain train Re
    9h 6m
    €61–105

  6. Bus

    1. Take the bus from Messina to Salernobus bus N592 / ...
    2. Take the bus from Salerno to Iserniabus bus 433
    10h 59m
    €49–75

  7. Train to Catania–Fontanarossa Airport, fly to Fiumicino International Airport, train

    1. Take the train from Messina Centrale to Catania Centraletrain train
    2. Fly from Catania–Fontanarossa Airport (CTA) to Fiumicino International Airport (FCO)plane plane CTA - FCO
    3. Take the train from Roma Termini to Iserniatrain train
    8h 31m
    €59–172

  8. Train to Palermo Airport, fly to Naples Airport, train

    1. Take the train from Messina Centrale to Palermo Centraletrain train
    2. Fly from Palermo Airport (PMO) to Naples Airport (NAP)plane plane PMO - NAP
    3. Take the train from Caserta to Iserniatrain train
    9h 47m
    €62–238

  9. Train to Catania–Fontanarossa Airport, fly to Abruzzo Airport, bus

    1. Take the train from Messina Centrale to Catania Centraletrain train
    2. Fly from Catania–Fontanarossa Airport (CTA) to Abruzzo Airport (PSR)plane plane CTA - PSR
    3. Take the bus from Pescara Airport to San Salvo Marinabus bus
    4. Take the bus from San Salvo Marina to Iserniabus bus
    9h 25m
    €53–212

Catania–Fontanarossa Airport (CTA) to Naples Airport (NAP) flights

Calendar25Weekly Planes
Duration1h 10mAverage Duration
Ticket€20Cheapest Price
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Comparing Your Travel Options

Map of how to get from Messina to Isernia.ExpandLaunch map view
  • Distance: 547.3 km
  • Duration: 8h 4m

What companies run services between Messina, Italy and Isernia, Italy?

You can take a bus from Messina Centrale Station to Isernia via Caserta pzza Garibaldi and Caserta Terminal Bus in around 8h 49m. Alternatively, you can take a train from Messina Centrale to Isernia via Napoli Centrale in around 9h 6m.

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