There are 7 ways to get from Messina to Isernia by ferry, train, bus, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Ferry, train
best- Take the ferry from Messina Marittima to Villa S.Giovanniferry M1 / ...
- Take the train from Villa S.Giovanni to Napoli Afragolatrain Fr
- Take the train from Napoli Afragola to Iserniatrain Re
8hBus via Caserta
cheapest- Take the bus from Messina Centrale Station to Caserta pzza Garibaldibus Autoservizi Salemi S202
- Take the bus from Caserta Terminal Bus to Iserniabus 433
8h 49m€27–70Ferry, drive
- Take the ferry from Messina Marittima to Villa San Giovanniferry
- Drive from Villa San Giovanni to Iserniacar
6h 5m€87–132Train to Catania–Fontanarossa Airport, fly to Naples Airport, train
- Take the train from Messina Centrale to Catania Centraletrain
- Fly from Catania–Fontanarossa Airport (CTA) to Naples Airport (NAP)plane CTA - NAP
- Take the train from Caserta to Iserniatrain
8h 18m€54–176Bus
- Take the bus from Messina to Salernobus N592 / ...
- Take the bus from Salerno to Iserniabus 433
10h 59m€49–82Train to Catania–Fontanarossa Airport, fly to Fiumicino International Airport, train
- Take the train from Messina Centrale to Catania Centraletrain
- Fly from Catania–Fontanarossa Airport (CTA) to Fiumicino International Airport (FCO)plane CTA - FCO
- Take the train from Roma Termini to Iserniatrain
8h 39m€63–180Train to Palermo Airport, fly to Naples Airport, train
- Take the train from Messina Centrale to Palermo Centraletrain
- Fly from Palermo Airport (PMO) to Naples Airport (NAP)plane PMO - NAP
- Take the train from Caserta to Iserniatrain
9h 51m€71–209
Catania–Fontanarossa Airport (CTA) to Naples Airport (NAP) flights
Questions & Answers
The cheapest way to get from Messina to Isernia is to bus via Caserta which costs €27 - €70 and takes 8h 49m.
The fastest way to get from Messina to Isernia is to ferry and drive which takes 6h 5m and costs €85 - €140.
No, there is no direct bus from Messina station to Isernia. However, there are services departing from Messina Centrale Station and arriving at Isernia via Caserta Terminal Bus. The journey, including transfers, takes approximately 8h 49m.
The distance between Messina and Isernia is 547 km.
The best way to get from Messina to Isernia without a car is to ferry and train which takes 8h and costs .
It takes approximately 8h to get from Messina to Isernia, including transfers.
Messina to Isernia bus services, operated by Autoservizi Salemi Srl, depart from Messina Centrale Station.
Messina to Isernia bus services, operated by Autoservizi Salemi Srl, arrive at Caserta pzza Garibaldi station.
Book your Messina to Isernia bus tickets online with Omio.
There are 477+ hotels available in Isernia.
What companies run services between Messina, Italy and Isernia, Italy?
You can take a bus from Messina Centrale Station to Isernia via Caserta pzza Garibaldi and Caserta Terminal Bus in around 8h 49m.
- Website
- ryanair.com
Flights from Catania–Fontanarossa Airport to Naples Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €26–110
Flights from Catania–Fontanarossa Airport to Fiumicino International Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €24–85
Flights from Palermo Airport to Naples Airport
- Ave. Duration
- 1h
- When
- Every day
- Estimated price
- €30–140
- Website
- ita-airways.com
Flights from Catania–Fontanarossa Airport to Fiumicino International Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- €45–100
- Website
- easyjet.com
Flights from Catania–Fontanarossa Airport to Naples Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €27–130
Flights from Palermo Airport to Naples Airport
- Ave. Duration
- 1h 1m
- When
- Every day
- Estimated price
- €29–130
- Website
- aeroitalia.com
Flights from Catania–Fontanarossa Airport to Fiumicino International Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €24–320
- Website
- flexflight.dk
Flights from Catania–Fontanarossa Airport to Fiumicino International Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €24–320
- Website
- volotea.com
Flights from Catania–Fontanarossa Airport to Fiumicino International Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €45–100
Flights from Palermo Airport to Naples Airport
- Ave. Duration
- 1h
- When
- Friday and Sunday
- Estimated price
- €21–90
- Website
- neosair.it
Flights from Catania–Fontanarossa Airport to Fiumicino International Airport
- Ave. Duration
- 1h 20m
- When
- Sunday
- Estimated price
- €100–300
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Villa S.Giovanni to Napoli Afragola
- Ave. Duration
- 4h 4m
- Frequency
- Hourly
- Estimated price
- €60–130
- Schedules at
- trenitalia.com
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Villa S.Giovanni to Napoli Afragola
- Ave. Duration
- 4h 53m
- Frequency
- Once daily
- Estimated price
- €50–110
- Website
- https://www.italotreno.it/en
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Napoli Afragola to Isernia
- Ave. Duration
- 1h 49m
- Frequency
- Every 4 hours
- Estimated price
- €14–24
- Website
- https://www.trenitalia.com/en.html
Train from Messina Centrale to Catania Centrale
- Ave. Duration
- 2h 1m
- Frequency
- Every 30 minutes
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Train from Caserta to Isernia
- Ave. Duration
- 1h 17m
- Frequency
- Every 3 hours
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Train from Messina Centrale to Catania Centrale
- Ave. Duration
- 2h 1m
- Frequency
- Every 30 minutes
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Isernia
- Ave. Duration
- 2h 16m
- Frequency
- Every 3 hours
- Estimated price
- €23–40
- Website
- https://www.trenitalia.com/en.html
Train from Messina Centrale to Palermo Centrale
- Ave. Duration
- 2h 56m
- Frequency
- Hourly
- Estimated price
- €27–45
- Website
- https://www.trenitalia.com/en.html
Train from Caserta to Isernia
- Ave. Duration
- 1h 17m
- Frequency
- Every 3 hours
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Messina Centrale to Catania Centrale
- Ave. Duration
- 1h 19m
- Frequency
- 4 times a day
- Estimated price
- €10–21
- Website
- https://www.trenitalia.com/en.html
Train from Messina Centrale to Catania Centrale
- Ave. Duration
- 1h 19m
- Frequency
- 4 times a day
- Estimated price
- €10–21
- Website
- https://www.trenitalia.com/en.html
Train from Messina Centrale to Palermo Centrale
- Ave. Duration
- 3h 10m
- Frequency
- 4 times a day
- Estimated price
- €23–50
- Website
- https://www.trenitalia.com/en.html
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Messina Centrale Station to Caserta pzza Garibaldi
- Ave. Duration
- 6h 35m
- Frequency
- Twice daily
- Estimated price
- €21–30
- Schedules at
- autoservizisalemi.it
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Messina Centrale Station to Caserta pzza Garibaldi
- Ave. Duration
- 7h 49m
- Frequency
- Once daily
- Estimated price
- €30–60
- Website
- https://www.itabus.it/en/home
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- https://www.flixbus.fr
Bus from Caserta Terminal Bus to Isernia
- Ave. Duration
- 1h 14m
- Frequency
- Once daily
- Estimated price
- €6–11
- Website
- https://www.flixbus.co.uk
Bus from Messina to Salerno
- Ave. Duration
- 6h 25m
- Frequency
- Twice daily
- Estimated price
- €35–60
- Website
- https://www.flixbus.co.uk
Bus from Salerno to Isernia
- Ave. Duration
- 3h 34m
- Frequency
- Once daily
- Estimated price
- €13–23
- Website
- https://www.flixbus.co.uk
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Ferry from Messina Marittima to Villa S.Giovanni
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- https://www.trenitalia.com/en.html
- Phone
- 3409848540
- info@blujetlines.it
- Website
- blujetlines.it
Ferry from Messina Marittima to Villa San Giovanni
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Estimated price
- €2–3
- Schedules at
- blujetlines.it
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