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How to get fromMessina to Iserniaby bus, ferry, train, car, plane or train (Trenitalia)

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There are 9 ways to get from Messina to Isernia by bus, ferry, train, car, plane, or train (Trenitalia)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus via Caserta

    best
    1. Take the bus from Messina Piazza della Repubblica to Caserta Viale Vittorio Venetobus bus Autoservizi Salemi S202
    2. Take the bus from Caserta Terminal Bus to Iserniabus bus 433
    8h 49m
    €26–44
  2. Bus

    cheapest
    1. Take the bus from Messina Main Train Station to Caserta Terminal Busbus bus Itabus
    2. Take the bus from Caserta Terminal Bus to Iserniabus bus 433
    10h 3m
    €25–42
  3. Ferry, train

    1. Take the ferry from Messina Marittima to Villa S.Giovanniferry ferry M1 / ...
    2. Take the train from Villa S.Giovanni to Napoli Centraletrain train Ic
    3. Take the train from Napoli Centrale to Iserniatrain train Re
    8h 53m
  4. Ferry, drive

    1. Take the ferry from Messina Marittima to Villa San Giovanniferry ferry
    2. Drive from Villa San Giovanni to Iserniacar car
    6h 5m
    €87–132
  5. Bus to Catania–Fontanarossa Airport, fly to Naples Airport, train

    1. Take the bus from Messina Viale Boccetta to Catania Fontanarossa Airport Departure Terminalbus bus
    2. Fly from Catania–Fontanarossa Airport (CTA) to Naples Airport (NAP)plane plane CTA - NAP
    3. Take the train from Napoli Centrale to Iserniatrain train
    6h 50m
    €40–157
  6. Train

    1. Take the train from Messina Centrale to Casertatrain train Ic
    2. Take the train from Caserta to Iserniatrain train Re
    9h 14m
    €37–63
  7. Ferry to Reggio Calabria Airport, fly to Fiumicino International Airport, train

    1. Take the ferry from Messina Marittima to Reggio di Calabriaferry ferry
    2. Fly from Reggio Calabria Airport (REG) to Fiumicino International Airport (FCO)plane plane REG - FCO
    3. Take the train from Roma Termini to Iserniatrain train
    7h 31m
    €70–221
  8. Bus to Catania–Fontanarossa Airport, fly to Fiumicino International Airport, train

    1. Take the bus from Messina Viale Boccetta to Catania Fontanarossa Airport Departure Terminalbus bus
    2. Fly from Catania–Fontanarossa Airport (CTA) to Fiumicino International Airport (FCO)plane plane CTA - FCO
    3. Take the train from Roma Termini to Iserniatrain train
    7h 35m
    €61–184
  9. Train to Palermo Airport, fly to Naples Airport, train

    1. Take the train from Messina Centrale to Palermo Centraletrain train
    2. Fly from Palermo Airport (PMO) to Naples Airport (NAP)plane plane PMO - NAP
    3. Take the train from Napoli Centrale to Iserniatrain train
    9h 36m
    €52–170

Messina to Isernia by bus

Calendar7Weekly Buses
Duration8h 49mAverage Duration
Ticket€26Cheapest Price
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Questions & Answers

What companies run services between Messina, Italy and Isernia, Italy?

You can take a bus from Messina Piazza della Repubblica to Isernia via Caserta Viale Vittorio Veneto and Caserta Terminal Bus in around 8h 49m. Alternatively, you can take a train from Messina Centrale to Isernia via Caserta in around 9h 14m.

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