There are 8 ways to get from Messina to Isernia by ferry, train, bus, car, plane, train (Trenitalia), or car ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Ferry, train
best- Take the ferry from Messina Marittima to Villa S.Giovanniferry M1 / ...
- Take the train from Villa S.Giovanni to Napoli Centraletrain Ic
- Take the train from Napoli Centrale to Iserniatrain Re
8h 55mBus
cheapest- Take the bus from Messina to Napoli P.zza Garibaldibus N590 / ...
- Take the bus from Napoli, Autostazione Metropark to Iserniabus 6
9h 30m€36–65Ferry, drive
- Take the ferry from Messina Marittima to Villa San Giovanniferry
- Drive from Villa San Giovanni to Iserniacar
6h 5m€87–132Train, fly to Naples Airport
- Take the train from Messina Centrale to Catania Centraletrain
- Fly from Catania–Fontanarossa Airport (CTA) to Naples Airport (NAP)plane CTA - NAP
- Take the train from Caserta to Iserniatrain
7h 59m€45–158Train (Trenitalia)
- Take the train from Messina Centrale to Casertatrain Ic
- Take the train from Caserta to Iserniatrain Re
8h 56m€58–125Car ferry, train
- Take the car ferry from Messina Marittima to Villa San Giovannicarferry
- Take the train from Villa San Giovanni to Napoli Centraletrain
- Take the train from Napoli Centrale to Iserniatrain Re
9h 7m€71–186Train, fly to Fiumicino International Airport
- Take the train from Messina Centrale to Catania Centraletrain
- Fly from Catania–Fontanarossa Airport (CTA) to Fiumicino International Airport (FCO)plane CTA - FCO
- Take the train from Roma Termini to Iserniatrain
8h 16m€67–211Train, fly to Abruzzo Airport, bus
- Take the train from Messina Centrale to Catania Centraletrain
- Fly from Catania–Fontanarossa Airport (CTA) to Abruzzo Airport (PSR)plane CTA - PSR
- Take the bus from Pescara to Iserniabus
9h 18m€64–236
Catania–Fontanarossa Airport (CTA) to Naples Airport (NAP) flights
Questions & Answers
The cheapest way to get from Messina to Isernia is to bus which costs €35 - €65 and takes 9h 30m.
The fastest way to get from Messina to Isernia is to ferry and drive which takes 6h 5m and costs €85 - €140.
No, there is no direct bus from Messina to Isernia. However, there are services departing from Messina and arriving at Isernia via Napoli, Autostazione Metropark. The journey, including transfers, takes approximately 9h 30m.
No, there is no direct train from Messina to Isernia. However, there are services departing from Messina Centrale and arriving at Isernia via Caserta. The journey, including transfers, takes approximately 8h 56m.
The distance between Messina and Isernia is 555 km.
The best way to get from Messina to Isernia without a car is to ferry and train which takes 8h 55m and costs .
It takes approximately 8h 55m to get from Messina to Isernia, including transfers.
Messina to Isernia bus services, operated by FlixBus, depart from Messina station.
Messina to Isernia train services, operated by Trenitalia Intercity, depart from Messina Centrale station.
The best way to get from Messina to Isernia is to bus which takes 9h 30m and costs €35 - €65. Alternatively, you can train, which costs €55 - €130 and takes 8h 56m.
What companies run services between Messina, Italy and Isernia, Italy?
You can take a bus from Messina to Isernia via Napoli P.zza Garibaldi and Napoli, Autostazione Metropark in around 9h 30m. Alternatively, you can take a train from Messina Centrale to Isernia via Caserta in around 8h 56m.
- Website
- ryanair.com
Flights from Catania–Fontanarossa Airport to Naples Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €23–120
Flights from Catania–Fontanarossa Airport to Fiumicino International Airport
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- €25–130
Flights from Catania–Fontanarossa Airport to Abruzzo Airport
- Ave. Duration
- 1h 25m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €45–190
- Website
- ita-airways.com
Flights from Catania–Fontanarossa Airport to Fiumicino International Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- €35–140
- Website
- aeroitalia.com
Flights from Catania–Fontanarossa Airport to Fiumicino International Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €30–130
- Website
- flexflight.dk
Flights from Catania–Fontanarossa Airport to Fiumicino International Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €30–130
- Website
- easyjet.com
Flights from Catania–Fontanarossa Airport to Naples Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €21–110
- Website
- neosair.it
Flights from Catania–Fontanarossa Airport to Fiumicino International Airport
- Ave. Duration
- 1h 20m
- When
- Sunday
- Estimated price
- €140–450
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Villa S.Giovanni to Napoli Centrale
- Ave. Duration
- 4h 33m
- Frequency
- Every 4 hours
- Estimated price
- €40–100
- Website
- https://www.trenitalia.com/en.html
Train from Messina Centrale to Catania Centrale
- Ave. Duration
- 1h 19m
- Frequency
- Twice daily
- Estimated price
- €9–21
- Website
- https://www.trenitalia.com/en.html
Train from Messina Centrale to Caserta
- Ave. Duration
- 6h 38m
- Frequency
- 5 times a week
- Estimated price
- €45–110
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Villa S.Giovanni to Napoli Centrale
- Ave. Duration
- 4h 12m
- Frequency
- Twice daily
- Estimated price
- €60–120
- Schedules at
- trenitalia.com
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Villa S.Giovanni to Napoli Centrale
- Ave. Duration
- 4h 34m
- Frequency
- 4 times a day
- Estimated price
- €50–110
- Website
- https://www.italotreno.it/en
Train from Villa San Giovanni to Napoli Centrale
- Ave. Duration
- 4h 34m
- Frequency
- Once daily
- Estimated price
- €55–120
- Website
- https://www.italotreno.it/en
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Napoli Centrale to Isernia
- Ave. Duration
- 2h 3m
- Frequency
- 4 times a day
- Estimated price
- €15–27
- Website
- https://www.trenitalia.com/en.html
Train from Messina Centrale to Catania Centrale
- Ave. Duration
- 1h 48m
- Frequency
- Hourly
- Estimated price
- €11–20
- Website
- https://www.trenitalia.com/en.html
Train from Caserta to Isernia
- Ave. Duration
- 1h 18m
- Frequency
- 5 times a day
- Estimated price
- €11–20
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Isernia
- Ave. Duration
- 2h 8m
- Frequency
- 5 times a day
- Estimated price
- €23–40
- Website
- https://www.trenitalia.com/en.html
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Messina to Napoli P.zza Garibaldi
- Ave. Duration
- 6h 35m
- Frequency
- Twice daily
- Estimated price
- €30–55
- Website
- https://www.flixbus.co.uk
Bus from Pescara to Isernia
- Ave. Duration
- 2h 29m
- Frequency
- Once daily
- Estimated price
- €11–20
- Website
- https://www.flixbus.co.uk
- Phone
- 0865.221788
- info@satiautobus.com
- Website
- satiautobus.com
Bus from Napoli, Autostazione Metropark to Isernia
- Ave. Duration
- 1h 50m
- Frequency
- 3 times a day
- Estimated price
- €4–10
- Schedules at
- satiautobus.com
- Phone
- +39 0874 64744
- info@atm-molise.it
- Website
- atm-molise.it
Bus from Pescara to Isernia
- Ave. Duration
- 2h 15m
- Frequency
- Twice daily
- Estimated price
- €8–13
- Schedules at
- atm-molise.it
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Ferry from Messina Marittima to Villa S.Giovanni
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- https://www.trenitalia.com/en.html
- Phone
- 3409848540
- info@blujetlines.it
- Website
- blujetlines.it
Ferry from Messina Marittima to Villa San Giovanni
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Estimated price
- €2–3
- Schedules at
- blujetlines.it
- Phone
- +39.090.57.37
- servizioclienti@carontetourist.it
- Website
- carontetourist.it
Car ferry from Messina Marittima to Villa San Giovanni
- Ave. Duration
- 30 min
- Frequency
- Hourly
- Estimated price
- €1–39
- Schedules at
- carontetourist.it
- Passenger
- €3
- Car
- €39
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More Questions & Answers
Messina to Isernia bus services, operated by FlixBus, arrive at Napoli P.zza Garibaldi station.
Messina to Isernia train services, operated by Trenitalia Intercity, arrive at Caserta station.
Book your Messina to Isernia train tickets online with Omio.
Book your Messina to Isernia bus tickets online with Omio.
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