The average train between Lucca and Isernia takes 6h 57m and the fastest train takes 5h 52m. The train service runs several times per day from Lucca to Isernia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Lucca and Isernia. The earliest departure is at 5:05 AM in the morning, and the last departure from Lucca is at 8:31 PM which arrives into Isernia at 8:27 AM. All services require a transfer at Firenze S.M.N. and take an average of 6h 57m. The schedules shown below are for the next available departures.


6h 10m • 2 changes

5h 52m • 2 changes

6h 8m • 2 changes

5h 55m • 2 changesWant to know about travelling from Lucca to Isernia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Lucca to Isernia. However, there are services departing from Lucca station and arriving at Isernia station via Firenze S.M.N. station and Roma Termini station. The journey, including transfers, takes approximately 6h 57m.
Lucca to Isernia train services, operated by Trenitalia, depart from Lucca station.
Lucca to Isernia train services, operated by Trenitalia, arrive at Isernia station.
Book your Lucca to Isernia train tickets online with Omio.
The distance between Lucca and Isernia is 394 km. The road distance is 502 km.
You can take a train from Lucca to Isernia via Firenze S.M.N. and Roma Termini in around 6h 13m.