The average train between Isernia and Perugia takes 8h 28m and the fastest train takes 5h 50m. The train service runs several times per day from Isernia to Perugia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Isernia and Perugia. The earliest departure is at 6:35 AM in the morning, and the last departure from Isernia is at 8:35 PM which arrives into Perugia at 9:40 AM. All services require a transfer at Roma Termini and take an average of 8h 28m. The schedules shown below are for the next available departures.


6h 56m • 2 changes


7h 5m • 2 changes
Arrives next day


12h 13m • 2 changes
Arrives next day


12h 9m • 2 changes


5h 50m • 2 changes


6h 32m • 2 changes


6h 42m • 2 changes
Arrives next day


11h 40m • 2 changes


5h 50m • 2 changes


6h 32m • 2 changes


6h 42m • 2 changes
Arrives next day


11h 40m • 2 changes


5h 50m • 2 changes


6h 32m • 2 changes


6h 42m • 2 changes
Arrives next day


11h 40m • 2 changes


5h 50m • 2 changes


6h 32m • 2 changes


6h 42m • 2 changes
Arrives next day


11h 40m • 2 changes


5h 50m • 2 changes


6h 32m • 2 changes


6h 42m • 2 changes
Arrives next day


11h 40m • 2 changes
Want to know about travelling from Isernia to Perugia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Isernia to Perugia. However, there are services departing from Isernia station and arriving at Perugia station via Roma Termini. The journey, including transfers, takes approximately 8h 28m.
Isernia to Perugia train services, operated by Trenitalia, depart from Isernia station.
Isernia to Perugia train services, operated by Trenitalia, arrive at Foligno station.
Book your Isernia to Perugia train tickets online with Trenitalia and Trenitalia Intercity.
The distance between Isernia and Perugia is 226.7 km. The road distance is 375 km.
You can take a train from Isernia to Perugia via Roma Termini and Foligno in around 5h 30m.