Rome2Rio

Isernia to Palermo trains

Find Transport to Palermo

View schedule

Trip Overview

The train between Isernia and Palermo takes 24h 3m. The train runs, on average, once a week from Isernia to Palermo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

24h 3m
Duration
768 km
Distance
€102
Average price
Once a week
Frequency

Isernia to Palermo train times

Trains run once a week between Isernia and Palermo. The service departs Isernia at 7:01 PM in the evening, which arrives into Palermo at 19:04:00. All services require a transfer, and take on average 24h 3m. The schedules shown below are for the next available departures.

Departing Saturday, November 7, 2026

  •  → 

    Arrives next day

    TrenitaliaTrenitalia Intercity24h 3m • 1 change

Frequently asked questions

Want to know about travelling from Isernia to Palermo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Isernia to Palermo.ExpandLaunch map view
  • Distance: 768.4 km
  • Duration: 24h 3m

What companies run services between Isernia, Italy and Palermo, Italy?

You can take a train from Isernia to Palermo Centrale via Napoli Afragola in around 12h 17m.

Operators