The average train between Isernia and Brussels takes 23h 37m and the fastest train takes 23h 6m. There is at least one train per day from Isernia to Brussels. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run once daily between Isernia and Brussels. The earliest departure is at 8:38 AM in the morning, and the last departure from Isernia is at 3:03 PM which arrives into Brussels at 3:48 PM. All services require a transfer at Roma Termini and take an average of 23h 37m. The schedules shown below are for the next available departures.
Want to know about travelling from Isernia to Brussels? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Isernia to Brussels. However, there are services departing from Isernia station and arriving at Brussels station via Roma Termini. The journey, including transfers, takes approximately 23h 37m.
Isernia to Brussels train services, operated by Trenitalia, depart from Isernia station.
Isernia to Brussels train services, operated by Trenitalia, arrive at Brussel-Zuid station.
Book your Isernia to Brussels train tickets online with Trenitalia, ItaloTreno and 2 other operators.
The distance between Isernia and Brussels is 1,277.2 km. The road distance is 1,950 km.
You can take a train from Isernia to Brussel-Zuid via Roma Termini, Milano Centrale, Paris Gare de Lyon, and Paris Nord in around 16h 13m.