There are 5 ways to get from Murrells Inlet to Louisville by plane, bus (Greyhound, Flixbus, Amtrak), car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Louisville International Airport
best- Fly from Myrtle Beach (MYR) to Louisville International Airport (SDF)plane MYR - SDF
3h 10m$112–491Bus via Atlanta
- Take the bus from Myrtle Beach Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Nashville Bus Stationbus
- Take the bus from Nashville to Louisville, KYbus
19h 11m$158–301Drive 618.1 mi
- Drive from Murrells Inlet to Louisvillecar 618.1 mi
12h 44m$113–163Fly to Blue Grass Airport, drive
- Fly from Myrtle Beach (MYR) to Blue Grass Airport (LEX)plane MYR - LEX
- Drive from Lexington-Airport-LEX to Louisvillecar
3h 7m$154–717Bus
- Take the bus from Myrtle Beach Bus Station to Fayetteville Bus Stationbus
- Take the bus from Fayetteville to High Point Terminalbus
- Take the bus from Winston Salem(Trans Center) to Columbus - Mound Stbus
- Take the bus from Columbus - Downtown - Mound St to Louisville, KY Bus Stationbus
30h 6m$173–351
Myrtle Beach (MYR) to Louisville International Airport (SDF) flights
Questions & Answers
The cheapest way to get from Murrells Inlet to Louisville is to drive which costs $110 - $170 and takes 12h 44m.
The fastest way to get from Murrells Inlet to Louisville is to fly and drive which takes 3h 7m and costs $150 - $750.
The distance between Murrells Inlet and Louisville is 514 miles. The road distance is 621.7 miles.
The best way to get from Murrells Inlet to Louisville without a car is to bus via Atlanta which takes 19h 11m and costs $150 - $310.
It takes approximately 3h 10m to get from Murrells Inlet to Louisville, including transfers.
The best way to get from Murrells Inlet to Louisville is to fly which takes 3h 10m and costs $110 - $500. Alternatively, you can bus via Atlanta, which costs $150 - $310 and takes 19h 11m.
Yes, the driving distance between Murrells Inlet to Louisville is 622 miles. It takes approximately 12h 44m to drive from Murrells Inlet to Louisville.
There are 544+ hotels available in Louisville.
What companies run services between Murrells Inlet, SC, USA and Louisville, KY, USA?
Allegiant Air, Delta, and two other airlines fly from Myrtle Beach (MYR) to Louisville International Airport (SDF) 4 times a day. Alternatively, you can take a vehicle from Murrells Inlet to Louisville, KY via Myrtle Beach Bus Station, Atlanta Bus Station, and Nashville in around 19h 11m.
- Website
- allegiantair.com
Flights from Myrtle Beach to Louisville International Airport
- Ave. Duration
- 1h 37m
- When
- Saturday
- Estimated price
- $70–440
Flights from Myrtle Beach to Blue Grass Airport
- Ave. Duration
- 1h 26m
- When
- Thursday and Sunday
- Estimated price
- $100–650
- Website
- delta.com
Flights from Myrtle Beach to Louisville International Airport via Atlanta
- Ave. Duration
- 3h 53m
- When
- Every day
- Estimated price
- $85–480
- Website
- aa.com
Flights from Myrtle Beach to Louisville International Airport via Charlotte
- Ave. Duration
- 3h 47m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $70–440
Flights from Myrtle Beach to Blue Grass Airport via Charlotte
- Ave. Duration
- 3h 52m
- When
- Saturday
- Estimated price
- $100–650
- Website
- southwest.com
Flights from Myrtle Beach to Louisville International Airport via Nashville
- Ave. Duration
- 3h 50m
- When
- Sunday
- Estimated price
- $85–480
Flights from Myrtle Beach to Louisville International Airport via Baltimore
- Ave. Duration
- 4h 5m
- When
- Tuesday, Wednesday, and Saturday
- Estimated price
- $110–550
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Myrtle Beach Bus Station to Atlanta Bus Station
- Ave. Duration
- 8h 55m
- Frequency
- Once daily
- Estimated price
- $55–120
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Nashville Bus Station
- Ave. Duration
- 4h 15m
- Frequency
- Every 4 hours
- Estimated price
- $35–80
- Website
- https://www.greyhound.com/
Bus from Myrtle Beach Bus Station to Fayetteville Bus Station
- Ave. Duration
- 8h 40m
- Frequency
- Once daily
- Estimated price
- $55–120
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Atlanta Bus Station to Nashville Bus Station
- Ave. Duration
- 4h 11m
- Frequency
- 3 times a day
- Estimated price
- $30–55
- Schedules at
- flixbus.com
Rome2Rio's guide to Amtrak Thruway
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Nashville to Louisville, KY
- Ave. Duration
- 3h 40m
- Frequency
- Twice daily
- Estimated price
- $30–50
- Website
- https://www.amtrak.com/home.html
- Adult
- $30–50
- Phone
- +1 704-348-1200
- info@sunwaycharters.com
- Website
- sunwaycharters.com
Bus from Fayetteville to High Point Terminal
- Ave. Duration
- 2h 36m
- Frequency
- Once daily
- Estimated price
- $17–25
- Schedules at
- sunwaycharters.com
- Passenger
- $17–25
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- baronsbus.com
Bus from Winston Salem(Trans Center) to Columbus - Mound St
- Ave. Duration
- 9h 20m
- Frequency
- Once daily
- Estimated price
- $35–90
- Website
- https://baronsbus.com
Bus from Columbus - Downtown - Mound St to Louisville, KY Bus Station
- Ave. Duration
- 4h 26m
- Frequency
- Once daily
- Estimated price
- $21–60
- Website
- https://baronsbus.com
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