There are 7 ways to get from Key West to Louisville by plane, bus (Greyhound, Flixbus, Amtrak), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Louisville International Airport
best- Fly from Key West International Airport (EYW) to Louisville International Airport (SDF)plane EYW - SDF
5h 33m$163–817Fly to Blue Grass Airport, drive
cheapest- Fly from Key West International Airport (EYW) to Blue Grass Airport (LEX)plane EYW - LEX
- Drive from Lexington-Airport-LEX to Louisvillecar
5h 36m$125–583Bus
- Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus Lks
- Take the bus from Big Pine Key to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Nashville Bus Stationbus
- Take the bus from Nashville to Louisville, KYbus
30h 12m$147–349Drive 1,179.1 mi
- Drive from Key West to Louisvillecar 1,179.1 mi
21h 58m$216–311Fly to Covington, bus
- Fly from Key West International Airport (EYW) to Covington (CVG)plane EYW - CVG
- Take the bus from Cincinnati - Downtown to Louisville, KY Bus Stationbus
6h 55m$233–1,161Fly to Evansville, bus
- Fly from Key West International Airport (EYW) to Evansville (EVV)plane EYW - EVV
- Take the bus from Evansville, IN to Louisville, KYbus
8h 57m$167–644Bus via Tallahassee
- Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus Lks
- Take the bus from Big Pine Key to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Tallahasseebus
- Take the bus from Tallahassee to Nashville Bus Stationbus
- Take the bus from Nashville to Louisville, KYbus
32h 2m$177–379
Key West to Louisville by bus and foot
Questions & Answers
The cheapest way to get from Key West to Louisville is to bus which costs $140 - $350 and takes 30h 12m.
The fastest way to get from Key West to Louisville is to fly which takes 5h 33m and costs $160 - $850.
No, there is no direct bus from Key West to Louisville. However, there are services departing from N Roosevelt & 3rd Street and arriving at Louisville, KY via Big Pine Key, Miami Airport Station, Atlanta Bus Station and Nashville. The journey, including transfers, takes approximately 30h 12m.
The distance between Key West and Louisville is 985 miles. The road distance is 1186 miles.
The best way to get from Key West to Louisville without a car is to bus which takes 30h 12m and costs $140 - $350.
It takes approximately 5h 33m to get from Key West to Louisville, including transfers.
Key West to Louisville bus services, operated by Key West Transit, depart from N Roosevelt & 3rd Street station.
The best way to get from Key West to Louisville is to fly which takes 5h 33m and costs $160 - $850. Alternatively, you can bus, which costs $140 - $350 and takes 30h 12m.
Key West to Louisville bus services, operated by Key West Transit, arrive at Big Pine Key - Auto Store / NAPA MM30 station.
Yes, the driving distance between Key West to Louisville is 1186 miles. It takes approximately 21h 58m to drive from Key West to Louisville.
What companies run services between Key West, FL, USA and Louisville, KY, USA?
Delta, Allegiant Air, and two other airlines fly from Key West International Airport (EYW) to Louisville International Airport (SDF) 5 times a day. Alternatively, you can take a bus from N Roosevelt & 3rd Street to Louisville, KY via Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami Airport Station, Atlanta Bus Station, and Nashville in around 30h 12m.
- Website
- delta.com
Flights from Key West International Airport to Louisville International Airport via Atlanta
- Ave. Duration
- 5h 24m
- When
- Every day
- Estimated price
- $150–800
Flights from Key West International Airport to Blue Grass Airport via Atlanta
- Ave. Duration
- 4h 43m
- When
- Every day
- Estimated price
- $100–550
Flights from Key West International Airport to Covington via Atlanta
- Ave. Duration
- 5h 29m
- When
- Every day
- Estimated price
- $210–1,100
Flights from Key West International Airport to Evansville via Atlanta
- Ave. Duration
- 6h 39m
- When
- Every day
- Estimated price
- $100–550
- Website
- aa.com
Flights from Key West International Airport to Louisville International Airport via Miami
- Ave. Duration
- 8h 8m
- When
- Every day
- Estimated price
- $150–800
Flights from Key West International Airport to Blue Grass Airport via Charlotte
- Ave. Duration
- 5h 56m
- When
- Every day
- Estimated price
- $100–550
Flights from Key West International Airport to Blue Grass Airport via Miami
- Ave. Duration
- 6h 51m
- When
- Saturday
- Estimated price
- $100–550
Flights from Key West International Airport to Evansville via Charlotte
- Ave. Duration
- 6h 17m
- When
- Every day
- Estimated price
- $110–600
Flights from Key West International Airport to Evansville via Chicago O'Hare
- Ave. Duration
- 5h 57m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $140–650
Flights from Key West International Airport to Evansville via Dallas/Ft.Worth
- Ave. Duration
- 7h 54m
- When
- Every day
- Estimated price
- $150–700
- Website
- allegiantair.com
Flights from Key West International Airport to Louisville International Airport via St. Petersburg
- Ave. Duration
- 5h 28m
- When
- Thursday and Sunday
- Estimated price
- $150–800
Flights from Key West International Airport to Covington
- Ave. Duration
- 2h 43m
- When
- Monday and Friday
- Estimated price
- $210–1,100
Flights from Key West International Airport to Covington via St. Petersburg
- Ave. Duration
- 4h 49m
- When
- Wednesday and Friday
- Estimated price
- $210–1,100
- Website
- flybreeze.com
Flights from Key West International Airport to Louisville International Airport via Tampa
- Ave. Duration
- 9h 8m
- When
- Thursday and Sunday
- Estimated price
- $280–1,500
Flights from Key West International Airport to Evansville via Orlando
- Ave. Duration
- 7h
- When
- Monday and Friday
- Estimated price
- $200–1,100
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30
- Ave. Duration
- 54 min
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Big Pine Key to Miami Airport Station
- Ave. Duration
- 3h 35m
- Frequency
- 3 times a day
- Estimated price
- $30–65
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Atlanta Bus Station
- Ave. Duration
- 16h
- Frequency
- Once daily
- Estimated price
- $65–150
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Nashville Bus Station
- Ave. Duration
- 4h 45m
- Frequency
- Every 4 hours
- Estimated price
- $35–60
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Tallahassee
- Ave. Duration
- 13h 55m
- Frequency
- Once daily
- Estimated price
- $60–140
- Website
- https://www.greyhound.com/
Bus from Tallahassee to Nashville Bus Station
- Ave. Duration
- 10h 5m
- Frequency
- Once daily
- Estimated price
- $55–120
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Miami Airport Station to Atlanta Bus Station
- Ave. Duration
- 13h 10m
- Frequency
- Once daily
- Estimated price
- $50–170
- Schedules at
- flixbus.com
Bus from Atlanta Bus Station to Nashville Bus Station
- Ave. Duration
- 4h 20m
- Frequency
- 3 times a day
- Estimated price
- $35–55
- Schedules at
- flixbus.com
Bus from Miami Airport Station to Tallahassee
- Ave. Duration
- 9h 40m
- Frequency
- 6 times a week
- Estimated price
- $65–110
- Schedules at
- flixbus.com
Rome2Rio's guide to Amtrak Thruway
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Nashville to Louisville, KY
- Ave. Duration
- 3h 40m
- Frequency
- Twice daily
- Estimated price
- $30–50
- Website
- https://www.amtrak.com/home.html
- Adult
- $30–50
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- baronsbus.com
Bus from Cincinnati - Downtown to Louisville, KY Bus Station
- Ave. Duration
- 2h 4m
- Frequency
- Once daily
- Estimated price
- $9–45
- Website
- https://baronsbus.com
- Phone
- +1 502-368-5644 x 135
- Website
- ridewithmiller.com
Bus from Evansville, IN to Louisville, KY
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Estimated price
- $35–55
- Website
- https://ridewithmiller.com
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