There are 4 ways to get from Murrells Inlet to Spartanburg by plane, car, bus, train, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Myrtle Beach (MYR) to Greenville–Spartanburg International Airport (GSP)plane MYR - GSP
3h 59m$397–710Drive 224.7 mi
cheapest- Drive from Murrells Inlet to Spartanburgcar 224.7 mi
5h 22m$41–60Drive, bus, train
- Drive from Murrells Inlet to Florence Bus Stationcar
- Take the bus from Florence Bus Station to Charlotte Bus Stationbus
- Take the train from Charlotte Amtrak Station to Spartanburg Stationtrain
7h 32m$64–96Bus
- Take the bus from Myrtle Beach Bus Station to Wilmington Cape Fear Public Transitbus
- Take the bus from Wilmington Cape Fear Public Transit to Charlotte Bus Stationbus
- Take the bus from Charlotte Bus Station to Spartanburgbus
11h 46m$118–182
Myrtle Beach (MYR) to Greenville–Spartanburg International Airport (GSP) flights
Questions & Answers
The cheapest way to get from Murrells Inlet to Spartanburg is to drive which costs $40 - $60 and takes 5h 22m.
The fastest way to get from Murrells Inlet to Spartanburg is to fly which takes 3h 59m and costs $390 - $750.
The distance between Murrells Inlet and Spartanburg is 239 miles. The road distance is 226.1 miles.
The best way to get from Murrells Inlet to Spartanburg without a car is to bus which takes 11h 46m and costs $110 - $190.
It takes approximately 3h 59m to get from Murrells Inlet to Spartanburg, including transfers.
The best way to get from Murrells Inlet to Spartanburg is to fly which takes 3h 59m and costs $390 - $750. Alternatively, you can bus, which costs $110 - $190 and takes 11h 46m.
Yes, the driving distance between Murrells Inlet to Spartanburg is 226 miles. It takes approximately 5h 22m to drive from Murrells Inlet to Spartanburg.
There are 71+ hotels available in Spartanburg.
What companies run services between Murrells Inlet, SC, USA and Spartanburg, SC, USA?
Delta, American Airlines, and Southwest Airlines fly from Myrtle Beach (MYR) to Greenville–Spartanburg International Airport (GSP) every 4 hours. Alternatively, you can take a vehicle from Murrells Inlet to Spartanburg via Myrtle Beach Bus Station, Wilmington Cape Fear Public Transit, Charlotte Bus Station, and Spartanburg in around 11h 46m.
- Website
- aa.com
Flights from Myrtle Beach to Greenville–Spartanburg International Airport via Charlotte
- Ave. Duration
- 4h 21m
- When
- Every day
- Estimated price
- $50–380
Flights from Myrtle Beach to Greenville–Spartanburg International Airport via Reagan Washington
- Ave. Duration
- 6h 45m
- When
- Saturday
- Estimated price
- $90–500
- Website
- delta.com
Flights from Myrtle Beach to Greenville–Spartanburg International Airport via Atlanta
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- $70–430
- Website
- southwest.com
Flights from Myrtle Beach to Greenville–Spartanburg International Airport via Nashville
- Ave. Duration
- 6h 35m
- When
- Tuesday and Wednesday
- Estimated price
- $90–490
Flights from Myrtle Beach to Greenville–Spartanburg International Airport via Baltimore
- Ave. Duration
- 6h 50m
- When
- Thursday
- Estimated price
- $95–550
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Charlotte Amtrak Station to Spartanburg Station
- Ave. Duration
- 1h 26m
- Frequency
- Once daily
- Estimated price
- $27–35
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Florence Bus Station to Charlotte Bus Station
- Ave. Duration
- 2h 45m
- Frequency
- Once daily
- Estimated price
- $21–35
- Schedules at
- flixbus.com
Bus from Charlotte Bus Station to Spartanburg
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $18–27
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Myrtle Beach Bus Station to Wilmington Cape Fear Public Transit
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $14–22
- Website
- https://www.greyhound.com/
Bus from Wilmington Cape Fear Public Transit to Charlotte Bus Station
- Ave. Duration
- 6h 15m
- Frequency
- Once daily
- Estimated price
- $30–65
- Website
- https://www.greyhound.com/
Bus from Charlotte Bus Station to Spartanburg
- Ave. Duration
- 1h 20m
- Frequency
- 3 times a day
- Estimated price
- $17–24
- Website
- https://www.greyhound.com/
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