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How to get fromMurrells Inlet to Gatlinburgby plane, taxi, bus, car, or train

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There are 6 ways to get from Murrells Inlet to Gatlinburg by plane, taxi, bus, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Mcghee Tyson Airport, taxi

    best
    1. Fly from Myrtle Beach (MYR) to Mcghee Tyson Airport (TYS)plane plane MYR - TYS
    2. Take the taxi from Mcghee Tyson Airport (TYS) to Gatlinburgtaxi taxi
    4h 55m
    $291–808

  2. Drive 373.5 mi

    cheapest
    1. Drive from Murrells Inlet to Gatlinburgcar car 373.5 mi
    7h 35m
    $69–99

  3. Bus, drive via Wilmington (Greyhound)

    1. Take the bus from Myrtle Beach Bus Station to Wilmington Cape Fear Public Transitbus bus
    2. Take the bus from Wilmington Cape Fear Public Transit to Raleigh Bus Stationbus bus
    3. Take the bus from Raleigh Bus Station to Asheville, NCbus bus
    4. Drive from Asheville, NC to Gatlinburgcar car
    13h 59m
    $123–204

  4. Fly to Asheville Regional Airport, drive

    1. Fly from Myrtle Beach (MYR) to Asheville Regional Airport (AVL)plane plane MYR - AVL
    2. Drive from Asheville-Airport-AVL to Gatlinburgcar car
    5h 38m
    $96–341

  5. Drive, train, bus

    1. Drive from Murrells Inlet to Kingstree Stationcar car
    2. Take the train from Kingstree Station to Selma Stationtrain train
    3. Take the train from Selma Station to Greensborotrain train
    4. Take the bus from Greensboro Bus Stop to Asheville, NCbus bus
    5. Drive from Asheville, NC to Gatlinburgcar car
    14h 20m
    $141–268

  6. Bus, drive (Greyhound)

    1. Take the bus from Myrtle Beach Bus Station to Raleigh Bus Stationbus bus
    2. Take the bus from Raleigh Bus Station to Asheville, NCbus bus
    3. Drive from Asheville, NC to Gatlinburgcar car
    18h 39m
    $157–272

Myrtle Beach (MYR) to Mcghee Tyson Airport (TYS) flights

Calendar55Weekly Planes
Duration4h 49mAverage Duration
Ticket$82Cheapest Price
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Questions & Answers

Map of how to get from Murrells Inlet to Gatlinburg.ExpandLaunch map view
  • Distance: 375.2 mi
  • Duration: 4h 55m

What companies run services between Murrells Inlet, SC, USA and Gatlinburg, TN, USA?

There is no direct connection from Murrells Inlet to Gatlinburg. However, you can take the taxi to Myrtle Beach (MYR) airport, fly to Mcghee Tyson Airport (TYS), then take the taxi to Gatlinburg. Alternatively, you can take a vehicle from Murrells Inlet to Gatlinburg via Myrtle Beach Bus Station, Wilmington Cape Fear Public Transit, Raleigh Bus Station, and Asheville, NC in around 13h 59m.

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