What is the cheapest way to get from Murrells Inlet to Lake City?

The cheapest way to get from Murrells Inlet to Lake City is to drive which costs $65 - $100 and takes 6h 57m.

What is the fastest way to get from Murrells Inlet to Lake City?

The fastest way to get from Murrells Inlet to Lake City is to drive which takes 6h 57m and costs $65 - $100.

How far is it from Murrells Inlet to Lake City?

The distance between Murrells Inlet and Lake City is 437 miles. The road distance is 373.4 miles.

How do I travel from Murrells Inlet to Lake City without a car?

The best way to get from Murrells Inlet to Lake City without a car is to bus which takes 10h 26m and costs $110 - $270.

How long does it take to get from Murrells Inlet to Lake City?

It takes approximately 10h 6m to get from Murrells Inlet to Lake City, including transfers.

Can I drive from Murrells Inlet to Lake City?

Yes, the driving distance between Murrells Inlet to Lake City is 373 miles. It takes approximately 6h 57m to drive from Murrells Inlet to Lake City.

Where can I stay near Lake City?

There are 24+ hotels available in Lake City.

Murrells Inlet to Lake City - 8 ways to travel via train, car, bus, and plane

There are 8 ways to get from Murrells Inlet to Lake City by car, train, bus, bus (Greyhound, Flixbus), or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Drive, train, bus
best
1. Drive from Murrells Inlet to Kingstree Station
2. Take the train from Kingstree Station to Jacksonville
3. Take the bus from Jacksonville to Lake City Bus Station
10h 6m
$94–220
Drive 371.3 mi
cheapest
1. Drive from Murrells Inlet to Lake City371.3 mi
6h 57m
$68–98
Bus
1. Take the bus from Myrtle Beach, SC to Florence
2. Take the bus from Florence Bus Station to Jacksonville
3. Take the bus from Jacksonville to Lake City Bus Station
10h 26m
$117–263
Fly to Jacksonville, bus
1. Fly from Myrtle Beach (MYR) to Jacksonville (JAX)MYR - JAX
2. Take the bus from Jacksonville to Lake City Bus Station
7h 36m
$130–523
Bus, train
1. Take the bus from Myrtle Beach Bus Station to Charleston Bus Station
2. Take the train from Charleston Amtrak Station to Jacksonville
3. Take the bus from Jacksonville to Lake City Bus Station
11h 19m
$129–241
Fly to Gainesville Regional Airport, bus
1. Fly from Myrtle Beach (MYR) to Gainesville Regional Airport (GNV)MYR - GNV
2. Take the bus from Gainesville to Lake City Bus Station
7h 26m
$147–687
Fly to Orlando, bus
1. Fly from Myrtle Beach (MYR) to Orlando (MCO)MYR - MCO
2. Take the bus from Orlando Bus Station to Lake City Bus Station
7h 57m
$146–389
Fly to Valdosta, bus
1. Fly from Myrtle Beach (MYR) to Valdosta (VLD)MYR - VLD
2. Take the bus from Valdosta to Gainesville Bus Stop
3. Take the bus from Gainesville Bus Stop to Lake City Bus Station
10h 15m
$167–522

Myrtle Beach (MYR) to Jacksonville (JAX) flights

101Weekly Planes

4h 55mAverage Duration

$79Cheapest Price

See schedules

Questions & Answers

Map of how to get from Murrells Inlet to Lake City.

Launch map view

Distance: 434.4 mi
Duration: 10h 6m

What companies run services between Murrells Inlet, SC, USA and Lake City, FL, USA?

You can take a vehicle from Murrells Inlet to Lake City Bus Station via Myrtle Beach, SC, Florence, Florence Bus Station, and Jacksonville in around 10h 26m.

Airlines

Train operators

Bus operators

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