There are 8 ways to get from Independence to Louisville by train, bus, car, plane, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus
best- Take the train from Independence Station to St. Louistrain
- Take the bus from St Louis Bus Station to Evansville Bus Stationbus
- Take the bus from Evansville, IN to Louisville, KYbus
13h 11m$101–155Drive 498.5 mi
cheapest- Drive from Independence to Louisvillecar 498.5 mi
8h 22m$91–132Fly to Louisville International Airport
- Fly from Kansas City (MCI) to Louisville International Airport (SDF)plane MCI - SDF
8h 7m$191–1,103Bus
- Take the bus from Kansas City Bus Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Evansville Bus Stationbus
- Take the bus from Evansville, IN to Louisville, KYbus
13h 42m$98–160Fly to Blue Grass Airport, drive
- Fly from Kansas City (MCI) to Blue Grass Airport (LEX)plane MCI - LEX
- Drive from Lexington-Airport-LEX to Louisvillecar
8h 41m$103–519Fly to Indianapolis, bus
- Fly from Kansas City (MCI) to Indianapolis (IND)plane MCI - IND
- Take the bus from Indianapolis Union Station to Louisville, KYbus
9h 26m$202–523Fly to Nashville, bus
- Fly from Kansas City (MCI) to Nashville (BNA)plane MCI - BNA
- Take the bus from Nashville to Louisville, KYbus
10h 10m$182–512Fly to Covington, bus
- Fly from Kansas City (MCI) to Covington (CVG)plane MCI - CVG
- Take the bus from Cincinnati - Downtown to Louisville, KY Bus Stationbus
10h 53m$161–947
Independence to Louisville by train and bus
Questions & Answers
The cheapest way to get from Independence to Louisville is to drive which costs $90 - $140 and takes 8h 22m.
The fastest way to get from Independence to Louisville is to fly which takes 8h 7m and costs $190 - $1,100.
No, there is no direct bus from Independence to Louisville. However, there are services departing from On Truman At Main Westbound and arriving at Louisville, KY via Kansas City Bus Station, St Louis Bus Station and Evansville, IN. The journey, including transfers, takes approximately 13h 42m.
The distance between Independence and Louisville is 556 miles. The road distance is 501.4 miles.
The best way to get from Independence to Louisville without a car is to train and bus which takes 13h 11m and costs $100 - $160.
It takes approximately 13h 11m to get from Independence to Louisville, including transfers.
Independence to Louisville bus services, operated by Greyhound USA, depart from Kansas City Bus Station.
The best way to get from Independence to Louisville is to fly which takes 8h 7m and costs $190 - $1,100. Alternatively, you can bus, which costs $95 - $160 and takes 13h 42m.
Independence to Louisville bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Louisville is 1h ahead of Independence. It is currently 11:15 AM in Independence and 12:15 PM in Louisville.
What companies run services between Independence, MO, USA and Louisville, KY, USA?
Southwest Airlines flies from Kansas City (MCI) to Louisville International Airport (SDF) twice daily. Alternatively, you can take a bus from On Truman At Main Westbound to Louisville, KY via East Village - Bay A, Kansas City Bus Station, St Louis Bus Station, and Evansville, IN in around 13h 42m.
- Website
- southwest.com
Flights from Kansas City to Louisville International Airport via Chicago Midway
- Ave. Duration
- 3h 40m
- When
- Monday to Friday
- Estimated price
- $120–700
Flights from Kansas City to Louisville International Airport via Nashville
- Ave. Duration
- 3h 45m
- When
- Saturday
- Estimated price
- $120–700
Flights from Kansas City to Indianapolis
- Ave. Duration
- 1h 25m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $80–550
Flights from Kansas City to Indianapolis via Chicago Midway
- Ave. Duration
- 3h 41m
- When
- Every day
- Estimated price
- $90–550
Flights from Kansas City to Nashville
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $75–460
Flights from Kansas City to Nashville via St. Louis
- Ave. Duration
- 3h 33m
- When
- Every day
- Estimated price
- $75–460
Flights from Kansas City to Nashville via Chicago Midway
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- $95–550
Flights from Kansas City to Covington via Chicago Midway
- Ave. Duration
- 3h 30m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $150–900
Flights from Kansas City to Covington via Nashville
- Ave. Duration
- 5h 50m
- When
- Saturday and Sunday
- Estimated price
- $160–950
- Website
- delta.com
Flights from Kansas City to Blue Grass Airport via Atlanta
- Ave. Duration
- 4h 27m
- When
- Every day
- Estimated price
- $110–600
Flights from Kansas City to Blue Grass Airport via Detroit
- Ave. Duration
- 5h 31m
- When
- Every day
- Estimated price
- $100–550
Flights from Kansas City to Covington via Detroit
- Ave. Duration
- 5h 19m
- When
- Every day
- Estimated price
- $180–1,000
Flights from Kansas City to Covington via Atlanta
- Ave. Duration
- 4h 36m
- When
- Every day
- Estimated price
- $210–1,100
Flights from Kansas City to Covington via Minneapolis
- Ave. Duration
- 6h 18m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $200–1,100
- Website
- aa.com
Flights from Kansas City to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 4h 5m
- When
- Saturday
- Estimated price
- $90–500
Flights from Kansas City to Blue Grass Airport via Charlotte
- Ave. Duration
- 5h 5m
- When
- Every day
- Estimated price
- $110–600
Flights from Kansas City to Blue Grass Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 42m
- When
- Every day
- Estimated price
- $120–650
Flights from Kansas City to Covington via Chicago O'Hare
- Ave. Duration
- 5h 38m
- When
- Every day
- Estimated price
- $150–900
Flights from Kansas City to Covington via Charlotte
- Ave. Duration
- 6h 3m
- When
- Every day
- Estimated price
- $220–1,100
- Website
- united.com
Flights from Kansas City to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 5h
- When
- Every day
- Estimated price
- $90–500
Flights from Kansas City to Covington via Chicago O'Hare
- Ave. Duration
- 4h 21m
- When
- Every day
- Estimated price
- $150–900
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Independence Station to St. Louis
- Ave. Duration
- 5h 21m
- Frequency
- Twice daily
- Estimated price
- $35–60
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from St Louis Bus Station to Evansville Bus Station
- Ave. Duration
- 3h 35m
- Frequency
- Once daily
- Estimated price
- $28–40
- Website
- https://www.greyhound.com/
Bus from Kansas City Bus Station to St Louis Bus Station
- Ave. Duration
- 4h
- Frequency
- 4 times a day
- Estimated price
- $35–65
- Website
- https://www.greyhound.com/
- Phone
- +1 502-368-5644 x 135
- Website
- ridewithmiller.com
Bus from Evansville, IN to Louisville, KY
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Estimated price
- $35–55
- Website
- https://ridewithmiller.com
Rome2Rio's guide to Amtrak Thruway
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Indianapolis Union Station to Louisville, KY
- Ave. Duration
- 2h 25m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- https://www.amtrak.com/home.html
- Adult
- $22–45
Bus from Nashville to Louisville, KY
- Ave. Duration
- 3h 40m
- Frequency
- Twice daily
- Estimated price
- $30–50
- Website
- https://www.amtrak.com/home.html
- Adult
- $30–50
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- baronsbus.com
Bus from Cincinnati - Downtown to Louisville, KY Bus Station
- Ave. Duration
- 2h 4m
- Frequency
- Once daily
- Estimated price
- $9–45
- Website
- https://baronsbus.com
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More Questions & Answers
Yes, the driving distance between Independence to Louisville is 501 miles. It takes approximately 8h 22m to drive from Independence to Louisville.
There are 438+ hotels available in Louisville.














