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How to get fromIndependence to Louisvilleby train, bus, car, plane or bus (Greyhound)

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There are 8 ways to get from Independence to Louisville by train, bus, car, plane, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from Independence Station to St. Louistrain train
    2. Take the bus from St Louis Bus Station to Evansville Bus Stationbus bus
    3. Take the bus from Evansville, IN to Louisville, KYbus bus
    13h 11m
    $101–155
  2. Drive 498.5 mi

    cheapest
    1. Drive from Independence to Louisvillecar car 498.5 mi
    8h 22m
    $91–132
  3. Fly to Louisville International Airport

    1. Fly from Kansas City (MCI) to Louisville International Airport (SDF)plane plane MCI - SDF
    8h 7m
    $191–1,103
  4. Bus

    1. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Evansville Bus Stationbus bus
    3. Take the bus from Evansville, IN to Louisville, KYbus bus
    13h 42m
    $98–160
  5. Fly to Blue Grass Airport, drive

    1. Fly from Kansas City (MCI) to Blue Grass Airport (LEX)plane plane MCI - LEX
    2. Drive from Lexington-Airport-LEX to Louisvillecar car
    8h 41m
    $103–519
  6. Fly to Indianapolis, bus

    1. Fly from Kansas City (MCI) to Indianapolis (IND)plane plane MCI - IND
    2. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    9h 26m
    $202–523
  7. Fly to Nashville, bus

    1. Fly from Kansas City (MCI) to Nashville (BNA)plane plane MCI - BNA
    2. Take the bus from Nashville to Louisville, KYbus bus
    10h 10m
    $182–512
  8. Fly to Covington, bus

    1. Fly from Kansas City (MCI) to Covington (CVG)plane plane MCI - CVG
    2. Take the bus from Cincinnati - Downtown to Louisville, KY Bus Stationbus bus
    10h 53m
    $161–947

Independence to Louisville by train and bus

Calendar7Weekly Services
Duration13h 11mAverage Duration
Ticket$101Cheapest Price
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Questions & Answers

What companies run services between Independence, MO, USA and Louisville, KY, USA?

Southwest Airlines flies from Kansas City (MCI) to Louisville International Airport (SDF) twice daily. Alternatively, you can take a bus from On Truman At Main Westbound to Louisville, KY via East Village - Bay A, Kansas City Bus Station, St Louis Bus Station, and Evansville, IN in around 13h 42m.

Airlines
Train operators
Bus operators

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