Rome2Rio

How to get fromMurrells Inlet to Destinby plane, bus, taxi, or car

Find Transport to Destin

See all options

There are 6 ways to get from Murrells Inlet to Destin by plane, bus, taxi, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Myrtle Beach to Destin–Fort Walton Beach Airport

    best
    1. Fly from Myrtle Beach (MYR) to Destin–Fort Walton Beach Airport (VPS)plane plane MYR - VPS
    4h 11m
    $141–433

  2. Drive 565.4 mi

    cheapest
    1. Drive from Murrells Inlet to Destincar car 565.4 mi
    11h 39m
    $104–149

  3. Bus, taxi

    1. Take the bus from Myrtle Beach Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta to Mobilebus bus
    3. Take the bus from Loxley to Crestviewbus bus
    4. Take the taxi from Crestview to Destintaxi taxi
    18h 53m
    $291–419

  4. Fly Myrtle Beach to Northwest Florida Beaches International Airport, taxi

    1. Fly from Myrtle Beach (MYR) to Northwest Florida Beaches International Airport (ECP)plane plane MYR - ECP
    2. Take the taxi from Northwest Florida Beaches International Airport (ECP) to Destintaxi taxi
    4h 48m
    $221–528

  5. Fly Myrtle Beach to Pensacola International Airport, taxi

    1. Fly from Myrtle Beach (MYR) to Pensacola International Airport (PNS)plane plane MYR - PNS
    2. Take the taxi from Pensacola-Airport-PNS to Destintaxi taxi
    5h 23m
    $221–538

  6. Drive to Florence Regional Airport, fly to Destin–Fort Walton Beach Airport

    1. Drive from Murrells Inlet to Florence Regional Airport (FLO)car car
    2. Fly from Florence Regional Airport (FLO) to Destin–Fort Walton Beach Airport (VPS)plane plane FLO - VPS
    6h 40m
    $114–425

Myrtle Beach (MYR) to Destin–Fort Walton Beach Airport (VPS) flights

Calendar44Weekly Planes
Duration4h 9mAverage Duration
Ticket$60Cheapest Price
See schedules

Questions & Answers

Map of how to get from Murrells Inlet to Destin.ExpandLaunch map view
  • Distance: 526.8 mi
  • Duration: 4h 11m

What companies run services between Murrells Inlet, SC, USA and Destin, FL, USA?

Delta, American Airlines, and two other airlines fly from Myrtle Beach (MYR) to Destin–Fort Walton Beach Airport (VPS) every 4 hours.

Airlines
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound