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How to get fromIthaca to St. Louisby bus, plane, train, bus (Flixbus, Greyhound) or car

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There are 9 ways to get from Ithaca to St. Louis by bus, plane, train, bus (Flixbus, Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Syracuse Hancock International Airport, fly

    best
    1. Take the bus from Ithaca, NY to Syracuse Airport, NYbus
    2. Fly from Syracuse Hancock International Airport (SYR) to Lambert–St. Louis International Airport (STL)planeSYR - STL
    7h 52m
    $223–1,155

  2. Fly from Ithaca Tompkins Regional Airport

    cheapest
    1. Fly from Ithaca Tompkins Regional Airport (ITH) to Lambert–St. Louis International Airport (STL)planeITH - STL
    7h 22m
    $135–664

  3. Bus, train

    1. Take the bus from Ithaca to Syracuse Bus Stationbus
    2. Take the train from Syracuse Regional Transportation Center to Chicago Union Stationtrain
    3. Take the train from Chicago Union Station to St. Louistrain
    21h 8m
    $177–473

  4. Bus via Pittsburgh

    1. Take the bus from Ithaca to Buffalobus
    2. Take the bus from Buffalo to Pittsburghbus
    3. Take the bus from Pittsburgh Intermodal Station to St Louis Bus Stationbus
    26h 10m
    $137–464

  5. Drive 863.7 mi

    1. Drive from Ithaca to St. Louiscar863.7 mi
    15h 5m
    $158–228

  6. Bus to Rochester, fly

    1. Take the bus from Ithaca, NY to Rochester, NYbus
    2. Fly from Rochester (ROC) to Lambert–St. Louis International Airport (STL)planeROC - STL
    8h 27m
    $173–909

  7. Bus to Greater Binghamton Airport, fly

    1. Take the bus from Ithaca, NY to Binghamton, NYbus
    2. Fly from Greater Binghamton Airport (BGM) to Lambert–St. Louis International Airport (STL)planeBGM - STL
    8h 5m
    $178–748

  8. Bus to Elmira/Corning Regional Airport, fly

    1. Take the bus from Ithaca - Tioga Street and Seneca Street to Transit Center - PO Sidebus
    2. Fly from Elmira/Corning Regional Airport (ELM) to Lambert–St. Louis International Airport (STL)planeELM - STL
    8h 32m

  9. Bus

    1. Take the bus from Ithaca, NY to Binghamton, NYbus
    2. Take the bus from Binghamton to Newark Penn Stationbus
    3. Take the bus from Newark Penn Station to St Louis Bus Stationbus
    28h 10m
    $160–455

Ithaca to St. Louis by bus and train

Calendar6Weekly Services
Duration21h 8mAverage Duration
Ticket$177Cheapest Price
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Questions & Answers

What companies run services between Ithaca, NY, USA and St. Louis, MO, USA?

You can take a bus from Ithaca to St Louis Bus Station via Buffalo, Pittsburgh, and Pittsburgh Intermodal Station in around 26h 10m. Alternatively, United Airlines flies from Ithaca Tompkins Regional Airport (ITH) to Lambert–St. Louis International Airport (STL) once daily.

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