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How to get fromIthaca to St. Louisby plane, bus, train, bus (Flixbus, Greyhound) or car

Find Transport to St. Louis

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There are 9 ways to get from Ithaca to St. Louis by plane, bus, train, bus (Flixbus, Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Ithaca Tompkins Regional Airport

    best
    1. Fly from Ithaca Tompkins Regional Airport (ITH) to Lambert–St. Louis International Airport (STL)plane plane ITH - STL
    7h 30m
    $165–833

  2. Bus via Pittsburgh

    cheapest
    1. Take the bus from Ithaca to Buffalobus bus
    2. Take the bus from Buffalo to Pittsburghbus bus
    3. Take the bus from Pittsburgh Intermodal Station to St Louis Bus Stationbus bus
    26h 15m
    $155–393

  3. Bus, train

    1. Take the bus from Ithaca to Syracuse Bus Stationbus bus
    2. Take the train from Syracuse Regional Transportation Center to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Louistrain train
    21h 8m
    $217–502

  4. Drive 863.9 mi

    1. Drive from Ithaca to St. Louiscar car 863.9 mi
    15h 16m
    $158–228

  5. Bus to Rochester, fly

    1. Take the bus from Ithaca to Rochester, Nybus bus
    2. Fly from Rochester (ROC) to Lambert–St. Louis International Airport (STL)plane plane ROC - STL
    8h 4m
    $243–1,180

  6. Bus to Elmira/Corning Regional Airport, fly

    1. Take the bus from Ithaca - Tioga Street and Seneca Street to Transit Center - PO Sidebus bus
    2. Fly from Elmira/Corning Regional Airport (ELM) to Lambert–St. Louis International Airport (STL)plane plane ELM - STL
    8h 40m

  7. Bus to Greater Binghamton Airport, fly

    1. Take the bus from Ithaca to Binghamtonbus bus
    2. Fly from Greater Binghamton Airport (BGM) to Lambert–St. Louis International Airport (STL)plane plane BGM - STL
    10h 28m
    $184–858

  8. Bus to Syracuse Hancock International Airport, fly

    1. Take the bus from Ithaca to Syracuse Bus Stationbus bus
    2. Fly from Syracuse Hancock International Airport (SYR) to Lambert–St. Louis International Airport (STL)plane plane SYR - STL
    8h 36m
    $213–1,242

  9. Bus

    1. Take the bus from Ithaca to Binghamtonbus bus 231
    2. Take the bus from Binghamton to Newark Penn Stationbus bus
    3. Take the bus from Newark Penn Station to St Louis Bus Stationbus bus
    28h 15m
    $185–360

Ithaca to St. Louis by bus and train

Calendar5Weekly Services
Duration21h 8mAverage Duration
Ticket$217Cheapest Price
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Questions & Answers

What companies run services between Ithaca, NY, USA and St. Louis, MO, USA?

United Airlines flies from Ithaca Tompkins Regional Airport (ITH) to Lambert–St. Louis International Airport (STL) twice daily. Alternatively, you can take a bus from Ithaca to St Louis Bus Station via Buffalo, Pittsburgh, and Pittsburgh Intermodal Station in around 26h 15m.

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