There are 6 ways to get from Scranton to St. Louis by plane, bus (Greyhound), bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Wilkes-Barre/Scranton International Airport
best- Fly from Wilkes-Barre/Scranton International Airport (AVP) to Lambert–St. Louis International Airport (STL)AVP - STL
6h 1m$175–752Bus
cheapest- Take the bus from Scranton, PA to Harrisburg, PAOurBus
- Take the bus from Harrisburg Bus Station to St Louis Bus StationGreyhound US0421
22h 15m$110–274Bus, train
- Take the bus from Scranton to Syracuse Bus Station
- Take the train from Syracuse Regional Transportation Center to Chicago Union Station
- Take the train from Chicago Union Station to St. Louis
22h 18m$190–628Drive 883.4 mi
- Drive from Scranton to St. Louis883.4 mi
14h 36m$162–233Bus to Newark Liberty International Airport, fly
- Take the bus from Scranton to Newark Penn Station
- Fly from Newark Liberty International Airport (EWR) to Lambert–St. Louis International Airport (STL)EWR - STL
6h 51m$182–540Bus to Laguardia Airport, fly
- Take the bus from Scranton, PA to Port Authority Bus Terminal
- Fly from Laguardia Airport (LGA) to Lambert–St. Louis International Airport (STL)LGA - STL
7h 53m$204–541
Scranton to St. Louis by bus
Questions & Answers
The cheapest way to get from Scranton to St. Louis is to bus which costs $110 - $280 and takes 22h 15m.
The fastest way to get from Scranton to St. Louis is to fly which takes 6h 1m and costs $170 - $750.
No, there is no direct bus from Scranton to St. Louis station. However, there are services departing from Scranton, PA and arriving at St Louis Bus Station via Harrisburg Bus Station. The journey, including transfers, takes approximately 22h 15m.
The distance between Scranton and St. Louis is 821 miles. The road distance is 888.6 miles.
The best way to get from Scranton to St. Louis without a car is to bus which takes 22h 15m and costs $110 - $280.
It takes approximately 6h 1m to get from Scranton to St. Louis, including transfers.
Scranton to St. Louis bus services, operated by OurBus, depart from Scranton, PA station.
The best way to get from Scranton to St. Louis is to fly which takes 6h 1m and costs $170 - $750. Alternatively, you can bus, which costs $110 - $280 and takes 22h 15m.
Scranton to St. Louis bus services, operated by OurBus, arrive at Harrisburg, PA station.
St. Louis is 1h behind Scranton. It is currently 2:37 AM in Scranton and 1:37 AM in St. Louis.
What companies run services between Scranton, PA, USA and St. Louis, MO, USA?
United Airlines and American Airlines fly from Wilkes-Barre/Scranton International Airport (AVP) to Lambert–St. Louis International Airport (STL) every 4 hours. Alternatively, you can take a bus from Scranton, PA to St Louis Bus Station via Harrisburg, PA and Harrisburg Bus Station in around 22h 15m.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- southwest.com
Flights from Laguardia Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 2h 54m
- When
- Every day
- Estimated price
- $110–600
- Website
- united.com
Flights from Wilkes-Barre/Scranton International Airport to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 5h 12m
- When
- Every day
- Estimated price
- $130–700
Flights from Wilkes-Barre/Scranton International Airport to Lambert–St. Louis International Airport via Washington Dulles
- Ave. Duration
- 9h 43m
- When
- Every day
- Estimated price
- $130–700
Flights from Newark Liberty International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 2h 54m
- When
- Every day
- Estimated price
- $100–550
Flights from Newark Liberty International Airport to Lambert–St. Louis International Airport via Washington Dulles
- Ave. Duration
- 5h 8m
- When
- Every day
- Estimated price
- $100–550
- Website
- delta.com
Flights from Newark Liberty International Airport to Lambert–St. Louis International Airport via Detroit
- Ave. Duration
- 5h 17m
- When
- Every day
- Estimated price
- $100–550
Flights from Laguardia Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 2h 55m
- When
- Every day
- Estimated price
- $110–600
- Website
- aa.com
Flights from Wilkes-Barre/Scranton International Airport to Lambert–St. Louis International Airport via Charlotte
- Ave. Duration
- 6h 44m
- When
- Every day
- Estimated price
- $150–750
Flights from Wilkes-Barre/Scranton International Airport to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 7h 12m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- $130–700
Flights from Laguardia Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 2h 58m
- When
- Every day
- Estimated price
- $110–600
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Syracuse Regional Transportation Center to Chicago Union Station
- Ave. Duration
- 13h 7m
- Frequency
- Twice daily
- Estimated price
- $120–230
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to St. Louis
- Ave. Duration
- 4h 46m
- Frequency
- 5 times a day
- Estimated price
- $40–360
- Website
- https://www.amtrak.com/home.html
- Phone
- +1-844-800-6828
- pr@ourbus.com
- Website
- ourbus.com
Bus from Scranton, PA to Harrisburg, PA
- Ave. Duration
- 3h 10m
- Frequency
- Once daily
- Estimated price
- $20–65
- Website
- https://www.ourbus.com
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from Scranton, PA to Harrisburg, PA
- Ave. Duration
- 3h 10m
- Frequency
- Once daily
- Estimated price
- $24–75
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $24–70
- Flexible
- $45–75
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Harrisburg Bus Station to St Louis Bus Station
- Ave. Duration
- 18h 5m
- Frequency
- Twice daily
- Estimated price
- $90–200
- Website
- https://www.greyhound.com/
Bus from Scranton, PA to Port Authority Bus Terminal
- Ave. Duration
- 2h 30m
- Frequency
- Once daily
- Estimated price
- $30–90
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Scranton to Syracuse Bus Station
- Ave. Duration
- 2h 25m
- Frequency
- 4 times a day
- Estimated price
- $29–40
- Schedules at
- flixbus.com
Bus from Scranton to Newark Penn Station
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $29–55
- Schedules at
- flixbus.com
- Phone
- +1 800-233-8604
- Website
- martzbus.com
Bus from Scranton, PA to Port Authority Bus Terminal
- Ave. Duration
- 2h 45m
- Frequency
- Every 4 hours
- Estimated price
- $60–85
- Website
- https://martzbus.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
Yes, the driving distance between Scranton to St. Louis is 889 miles. It takes approximately 14h 36m to drive from Scranton to St. Louis.
Book your Scranton to St. Louis bus tickets online with Omio.
There are 368+ hotels available in St. Louis.













