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How to get fromScranton to St. Louisby plane, bus (Greyhound), bus, train or car

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There are 7 ways to get from Scranton to St. Louis by plane, bus (Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Wilkes-Barre/Scranton International Airport

    best
    1. Fly from Wilkes-Barre/Scranton International Airport (AVP) to Lambert–St. Louis International Airport (STL)plane plane AVP - STL
    6h 24m
    $215–952

  2. Bus

    cheapest
    1. Take the bus from Scranton, PA to Harrisburg, PAbus bus OurBus
    2. Take the bus from Harrisburg Bus Station to St Louis Bus Stationbus bus Greyhound US0421
    22h 15m
    $100–314

  3. Bus, train

    1. Take the bus from Scranton to Syracuse Bus Stationbus bus
    2. Take the train from Syracuse Regional Transportation Center to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Louistrain train
    22h 18m
    $145–483

  4. Drive 883.6 mi

    1. Drive from Scranton to St. Louiscar car 883.6 mi
    14h 44m
    $162–233

  5. Bus to Newark Liberty International Airport, fly

    1. Take the bus from Scranton to Newark Penn Stationbus bus
    2. Fly from Newark Liberty International Airport (EWR) to Lambert–St. Louis International Airport (STL)plane plane EWR - STL
    7h 8m
    $200–596

  6. Bus to Laguardia Airport, fly

    1. Take the bus from Scranton, PA to Port Authority Bus Terminalbus bus
    2. Fly from Laguardia Airport (LGA) to Lambert–St. Louis International Airport (STL)plane plane LGA - STL
    8h 3m
    $235–539

  7. Bus to John F. Kennedy International Airport, fly

    1. Take the bus from Scranton to New York Midtownbus bus
    2. Fly from John F. Kennedy International Airport (JFK) to Lambert–St. Louis International Airport (STL)plane plane JFK - STL
    7h 49m
    $164–748

Scranton to St. Louis by bus

Calendar14Weekly Buses
Duration22h 15mAverage Duration
Ticket$100Cheapest Price
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Questions & Answers

What companies run services between Scranton, PA, USA and St. Louis, MO, USA?

United Airlines and American Airlines fly from Wilkes-Barre/Scranton International Airport (AVP) to Lambert–St. Louis International Airport (STL) 5 times a day. Alternatively, you can take a bus from Scranton, PA to St Louis Bus Station via Harrisburg, PA and Harrisburg Bus Station in around 22h 15m.

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