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How to get fromCincinnati to St. Louisby bus (Flixbus, Greyhound), car, plane, bus (Greyhound) or bus

Find Transport to St. Louis

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There are 6 ways to get from Cincinnati to St. Louis by bus (Flixbus, Greyhound), car, plane, bus (Greyhound), or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Cincinnati to IndianapolisbusFlixBus 2514
    2. Take the bus from Indianapolis Union Station to St Louis Bus StationbusGreyhound US0421
    7h 24m
    $50–183

  2. Drive 346 mi

    1. Drive from Cincinnati to St. Louiscar346 mi
    5h 45m
    $64–92

  3. Fly from Covington

    1. Fly from Covington (CVG) to Lambert–St. Louis International Airport (STL)planeCVG - STL
    5h 46m
    $144–854

  4. Bus via Evansville

    1. Take the bus from Cincinnati - Downtown to Louisville, KY Bus Stationbus
    2. Take the bus from Louisville, KY to Evansville, INbus
    3. Take the bus from Evansville Bus Station to St Louis Bus Stationbus
    9h 54m
    $75–148

  5. Drive to Louisville International Airport, fly

    1. Drive from Cincinnati to Louisville-Airport-SDFcar
    2. Fly from Louisville International Airport (SDF) to Lambert–St. Louis International Airport (STL)planeSDF - STL
    5h 57m
    $132–731

  6. Bus to John Glenn Columbus International Airport, fly

    1. Take the bus from Cincinnati - Downtown to Columbus - Downtown - Mound Stbus
    2. Fly from John Glenn Columbus International Airport (CMH) to Lambert–St. Louis International Airport (STL)planeCMH - STL
    6h 38m
    $295–683

Cincinnati to St. Louis by bus and foot

Calendar6Weekly Services
Duration7h 24mAverage Duration
Ticket$50Cheapest Price
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Questions & Answers

What companies run services between Cincinnati, OH, USA and St. Louis, MO, USA?

You can take a bus from Cincinnati to St Louis Bus Station via Indianapolis and Indianapolis Union Station in around 7h 24m. Alternatively, Southwest Airlines, Delta, and two other airlines fly from Covington (CVG) to Lambert–St. Louis International Airport (STL) every 2 hours.

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