Rome2Rio

How to get fromPresque Isle to St. Louisby car, plane, bus, train, bus (Amtrak, Greyhound), or bus (Amtrak, Greyhound, Flixbus)

Find Transport to St. Louis

See all options

There are 7 ways to get from Presque Isle to St. Louis by car, plane, bus, train, bus (Amtrak, Greyhound), or bus (Amtrak, Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Fredericton International Airport, fly

    best
    1. Drive from Presque Isle to Fredericton-Airport-YFCcar car
    2. Fly from Fredericton International Airport (YFC) to Lambert–St. Louis International Airport (STL)plane plane YFC - STL
    10h 57m
    $200–842

  2. Fly from Presque Isle

    cheapest
    1. Fly from Presque Isle (PQI) to Lambert–St. Louis International Airport (STL)plane plane PQI - STL
    8h 31m
    $180–812

  3. Bus, train

    1. Take the bus from Presque Isle, Maine to Bangor, MEbus bus
    2. Take the bus from Bangor Transportation Center to Boston, MA - South Stationbus bus
    3. Take the train from Boston to Chicago Union Stationtrain train
    4. Take the train from Chicago Union Station to St. Louistrain train
    37h 58m
    $461–991

  4. Bus

    1. Take the bus from Presque Isle, Maine to Bangor, MEbus bus
    2. Take the bus from Bangor Transportation Center to Boston, MA - South Stationbus bus
    3. Take the bus from South Station to Port Authority Bus Terminalbus bus
    4. Take the bus from Port Authority Bus Terminal to St Louis Bus Stationbus bus
    38h 25m
    $256–511

  5. Drive 1,453.2 mi

    1. Drive from Presque Isle to St. Louiscar car 1,453.2 mi
    26h 43m
    $266–384

  6. Bus to Bangor, fly

    1. Take the bus from Presque Isle, Maine to Bangor, MEbus bus
    2. Fly from Bangor (BGR) to Lambert–St. Louis International Airport (STL)plane plane BGR - STL
    10h 32m
    $281–1,236

  7. Bus via Newark

    1. Take the bus from Presque Isle, Maine to Bangor, MEbus bus
    2. Take the bus from Bangor Transportation Center to Boston, MA - South Stationbus bus
    3. Take the bus from Boston to Newark Penn Stationbus bus
    4. Take the bus from Newark Penn Station to St Louis Bus Stationbus bus
    38h 40m
    $241–456

Presque Isle to St. Louis by bus and train

Calendar7Weekly Services
Duration37h 58mAverage Duration
Ticket$461Cheapest Price
See schedules

Questions & Answers

Map of how to get from Presque Isle to St. Louis.ExpandLaunch map view
  • Distance: 1,439.3 mi
  • Duration: 10h 57m

What companies run services between Presque Isle, ME, USA and St. Louis, MO, USA?

You can take a bus from Presque Isle, Maine to St Louis Bus Station via Bangor, ME, Bangor Transportation Center, Boston, MA - South Station, South Station, and Port Authority Bus Terminal in around 38h 25m. Alternatively, JetBlue Airways and Southwest Airlines fly from Presque Isle (PQI) to Lambert–St. Louis International Airport (STL) once daily.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers