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There are 4 ways to get from New Orleans to St. Louis by plane, train, night bus, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  3 h 54 min

  1. Fly from New Orleans (MSY) to St. Louis (STL) MSY - STL

$174 - $430

Cheapest option

Bus, night bus  •  17 h 30 min

  1. Take the bus from New Orleans, La to Baton Rouge, La
  2. Take the bus from Baton Rouge, La to Memphis, Tn
  3. Take the night bus from Memphis, Tn to St Louis, Mo

$84 - $222

2 alternative options

Train, night bus  •  16 h 26 min

  1. Take the train from New Orleans Union Passenger Terminal to Carbondale Amtrak Station City Of New Orleans
  2. Take the night bus from Carbondale Amtrak Station to St. Louis Gateway Station Amtrak Thruway Connecting Service

Drive  •  11 h 5 min

  1. Drive from New Orleans to St. Louis 680.4 miles

$65 - $100

Questions & Answers

The cheapest way to get from New Orleans to St. Louis is to drive which costs $65 - $100 and takes 11 h 5 min.

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The quickest way to get from New Orleans to St. Louis is to fly which costs $170 - $430 and takes 3 h 54 min.

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No, there is no direct bus from New Orleans to St. Louis. However, there are services departing from New Orleans, La and arriving at St Louis, Mo via Baton Rouge, La and Memphis, Tn. The journey, including transfers, takes approximately 17 h 30 min.

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The distance between New Orleans and St. Louis is 603 miles. The road distance is 680.4 miles.

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The best way to get from New Orleans to St. Louis without a car is to train and night bus which takes 16 h 26 min and costs .

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It takes approximately 3 h 54 min to get from New Orleans to St. Louis, including transfers.

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New Orleans to St. Louis bus services, operated by Greyhound USA, depart from New Orleans, La station.

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The quickest flight from New Orleans Airport to St. Louis Airport is the direct flight which takes 1 h 40 min.

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New Orleans to St. Louis bus services, operated by Greyhound USA, arrive at St Louis, Mo station.

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Yes, the driving distance between New Orleans to St. Louis is 680 miles. It takes approximately 11 h 5 min to drive from New Orleans to St. Louis.

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Map of how to get from New Orleans to St. Louis.
Launch map view
  • Distance: 602.8 miles
  • Duration: 3 h 54 min

What companies run services between New Orleans, LA, USA and St. Louis, MO, USA?

Southwest Airlines and Delta fly from New Orleans to St. Louis every 2 hours.

Airlines
Southwest Airlines
Website
southwest.com
Flights from New Orleans to St. Louis
Ave. Duration
1 h 45 min
When
Every day
Estimated price
$330 - $900
Flights from New Orleans to St. Louis via Nashville
Ave. Duration
3 h 45 min
When
Sunday
Estimated price
$330 - $900
Flights from New Orleans to St. Louis via Kansas City
Ave. Duration
3 h 45 min
When
Monday to Friday
Estimated price
$330 - $900
Flights from New Orleans to St. Louis via Dallas
Ave. Duration
4 h
When
Wednesday
Estimated price
$330 - $900
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from New Orleans Union Passenger Terminal to Carbondale Amtrak Station
Ave. Duration
13 h 26 min
Frequency
Twice daily
Estimated price
$85 - $250
Website
amtrak.com
Coach Seat
$85 - $130
Flexi Coach Seat
$150 - $230
Business Coach Seat
$170 - $250
Room
$370 - $550
Bus operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Night bus from Carbondale Amtrak Station to St. Louis Gateway Station
Ave. Duration
2 h
Frequency
Once daily
Website
amtrak.com
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from New Orleans, La to Baton Rouge, La
Ave. Duration
1 h 45 min
Frequency
Hourly
Estimated price
$14 - $35
Website
greyhound.com
Economy
$14 - $21
Flexible
$25 - $35
Bus from Baton Rouge, La to Memphis, Tn
Ave. Duration
8 h 5 min
Frequency
Once daily
Estimated price
$40 - $110
Website
greyhound.com
Economy
$40 - $70
Flexible
$75 - $110
Night bus from Memphis, Tn to St Louis, Mo
Ave. Duration
5 h 40 min
Frequency
Once daily
Estimated price
$30 - $80
Website
greyhound.com
Economy
$30 - $55
Flexible
$60 - $80

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

Southwest Airlines offers flights from New Orleans Airport to St. Louis Airport.

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There are 194+ hotels available in St. Louis. Prices start at $69 USD per night.

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The best way to get from New Orleans to New Orleans Airport is to Bus which takes 38 min and costs $1 - $17.

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