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How to get fromIthaca to Chicagoby bus, plane, train, bus (Flixbus, Greyhound) or car

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There are 9 ways to get from Ithaca to Chicago by bus, plane, train, bus (Flixbus, Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Syracuse Hancock International Airport, fly to Chicago O'Hare International Airport

    best
    1. Take the bus from Ithaca, NY to Syracuse Airport, NYbus
    2. Fly from Syracuse Hancock International Airport (SYR) to Chicago O'Hare International Airport (ORD)planeSYR - ORD
    6h 1m
    $112–557

  2. Bus

    cheapest
    1. Take the bus from Ithaca to Buffalobus
    2. Take the bus from Buffalo to Cleveland Bus Stationbus
    3. Take the bus from Cleveland Bus Station to Chicago Bus Stationbus
    16h 55m
    $86–266

  3. Bus, train

    1. Take the bus from Ithaca to Syracuse Bus StationbusFlixBus 2691
    2. Take the train from Syracuse Regional Transportation Center to Chicago Union StationtrainLake Shore Limited
    15h 22m
    $137–263

  4. Drive 658.4 mi

    1. Drive from Ithaca to Chicagocar658.4 mi
    11h 37m
    $121–174

  5. Bus to Rochester, fly to Chicago O'Hare International Airport

    1. Take the bus from Ithaca, NY to Rochester, NYbus
    2. Fly from Rochester (ROC) to Chicago O'Hare International Airport (ORD)planeROC - ORD
    6h 19m
    $152–521

  6. Bus to Rochester, fly to Chicago Midway International Airport

    1. Take the bus from Ithaca, NY to Rochester, NYbus
    2. Fly from Rochester (ROC) to Chicago Midway International Airport (MDW)planeROC - MDW
    5h 56m
    $107–561

  7. Bus to Buffalo Niagara International Airport, fly to Chicago Midway International Airport

    1. Take the bus from Ithaca, NY to Buffalo, NYbus
    2. Fly from Buffalo Niagara International Airport (BUF) to Chicago Midway International Airport (MDW)planeBUF - MDW
    6h 46m
    $117–670

  8. Bus to Buffalo Niagara International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Ithaca, NY to Buffalo, NYbus
    2. Fly from Buffalo Niagara International Airport (BUF) to Chicago O'Hare International Airport (ORD)planeBUF - ORD
    7h 6m
    $97–510

  9. Bus to Wilkes-Barre/Scranton International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Ithaca to Scrantonbus
    2. Fly from Wilkes-Barre/Scranton International Airport (AVP) to Chicago O'Hare International Airport (ORD)planeAVP - ORD
    7h 6m
    $112–473

Ithaca to Chicago by bus and train

Calendar7Weekly Services
Duration15h 22mAverage Duration
Ticket$137Cheapest Price
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Questions & Answers

What companies run services between Ithaca, NY, USA and Chicago, IL, USA?

You can take a bus from Ithaca to Chicago Bus Station via Buffalo and Cleveland Bus Station in around 16h 55m.

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