The average train between Popoli and Isernia takes 14h 41m and the fastest train takes 7h. The train service runs several times per day from Popoli to Isernia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Popoli and Isernia. The earliest departure is at 9:40 AM in the morning, and the last departure from Popoli is at 10:22 PM which arrives into Isernia at 8:27 AM. All services require a transfer at Sulmona and take an average of 14h 41m. The schedules shown below are for the next available departures.



7h • 3 changes
Arrives next day



16h 18m • 3 changes
Arrives next day



17h 55m • 3 changes



7h • 3 changes
Arrives next day



16h 18m • 3 changes
Arrives next day



17h 55m • 3 changes



7h • 3 changes
Arrives next day



16h 18m • 3 changes
Arrives next day



17h 55m • 3 changes
Arrives next day



17h 1m • 3 changes



7h • 3 changes
Arrives next day



16h 18m • 3 changes
Arrives +2 days



34h 5m • 3 changes
Want to know about travelling from Popoli to Isernia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Popoli to Isernia. However, there are services departing from Popoli station and arriving at Isernia station via Avezzano. The journey, including transfers, takes approximately 14h 41m.
Popoli to Isernia train services, operated by Trenitalia, depart from Sulmona station.
Popoli to Isernia train services, operated by Trenitalia, arrive at Isernia station.
Book your Popoli to Isernia train tickets online with Trenitalia.
The distance between Popoli and Isernia is 72.1 km. The road distance is 223 km.
You can take a train from Popoli-Vittorito to Isernia via Sulmona, Avezzano, and Cassino in around 6h 53m.