The average train between Geneva and Isernia takes 16h 1m and the fastest train takes 11h 13m. The train service runs several times per day from Geneva to Isernia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Geneva and Isernia. The earliest departure is at 5:27 AM in the morning, and the last departure from Geneva is at 6:27 PM which arrives into Isernia at 3:23 PM. All services require a transfer at Domodossola and take an average of 16h 1m. The schedules shown below are for the next available departures.



14h 59m • 3 changes
Arrives next day



19h • 3 changes
Arrives next day



20h 56m • 3 changes



11h 13m • 3 changes
Arrives next day



19h • 3 changes
Arrives next day



20h 56m • 3 changes



11h 13m • 3 changes



14h 59m • 3 changes
Arrives next day



19h • 3 changes
Arrives next day



20h 56m • 3 changes



11h 13m • 3 changes



14h 59m • 3 changes
Arrives next day



19h • 3 changes



11h 13m • 3 changes



12h 28m • 3 changes
Arrives next day



19h • 3 changes
Arrives next day



20h 56m • 3 changes
Want to know about travelling from Geneva to Isernia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Geneva to Isernia. However, there are services departing from Geneva station and arriving at Isernia station via Domodossola. The journey, including transfers, takes approximately 16h 1m.
Geneva to Isernia train services, operated by Swiss Federal Railways (SBB CFF FFS), depart from Genève station.
Geneva to Isernia train services, operated by Swiss Federal Railways (SBB CFF FFS), arrive at Isernia station.
Book your Geneva to Isernia train tickets online with Swiss Federal Railways (SBB CFF FFS), Trenord and 3 other operators.
The distance between Geneva and Isernia is 825.3 km. The road distance is 1,110 km.
You can take a train from Genève to Isernia via Domodossola, Rho Fiera Milano, Milano Rogoredo, and Roma Termini in around 11h 9m.