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How to get fromSpoleto to Iserniaby train (Trenitalia), bus or car

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There are 4 ways to get from Spoleto to Isernia by train (Trenitalia), bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Spoleto to Roma Tiburtinatrain train 4153 / ...
    2. Take the train from Roma Tiburtina to Iserniatrain train Re
    4h 38m
    €21–42
  2. Bus

    1. Take the bus from Palombara to Roma, Autostazione Tiburtinabus bus E433
    2. Take the bus from Roma, Autostazione Tiburtina to Iserniabus bus Rome Tiburtina
    6h 35m
    €23–55
  3. Drive 243.2 km

    1. Drive from Spoleto to Iserniacar car 243.2 km
    3h 36m
    €38–55
  4. Train via Rome

    1. Take the train from Spoleto to Roma Terminitrain train 4153 / ...
    2. Take the train from Roma Termini to Iserniatrain train Re
    4h 44m
    €21–67

Spoleto to Isernia by train

Calendar6Weekly Trains
Duration4h 38mAverage Duration
Ticket€21Cheapest Price
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Questions & Answers

What companies run services between Spoleto, Italy and Isernia, Italy?

You can take a train from Spoleto to Isernia via Roma Tiburtina in around 4h 38m. Alternatively, you can take a bus from Via Nursina to Isernia via Palombara and Roma, Autostazione Tiburtina in around 6h 35m.

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