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How to get fromMilan to Iserniaby train, bus, car, plane or train (Trenitalia)

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There are 11 ways to get from Milan to Isernia by train, bus, car, plane, or train (Trenitalia)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Milan Rogoredo to Roma Terminitrain9987 / ...
    2. Take the train from Roma Termini to IserniatrainRe
    6h 1m
    €57–137
  2. Bus via Termoli

    cheapest
    1. Take the bus from Milano - San Donato to Termoli AutostazionebusVieste
    2. Take the bus from Termoli Terminal Bus to IserniabusCb 014 / ...
    14h 7m
    €37–55
  3. Bus

    1. Take the bus from Milano, San Donato M3 to San Salvo MarinabusN424
    2. Take the bus from San Salvo Marina to IserniabusTermoli-Rome tiburtina
    10h 51m
    €40–100
  4. Drive 725.5 km

    1. Drive from Milan to Iserniacar725.5 km
    6h 40m
    €112–162
  5. Fly Milan Linate Airport to Naples Airport, train

    1. Fly from Milan Linate Airport (LIN) to Naples Airport (NAP)planeLIN - NAP
    2. Take the train from Napoli Centrale to Iserniatrain
    5h 57m
    €56–190
  6. Train via Milan Centrale

    1. Take the train from Milano Centrale to Roma TerminitrainFr / ...
    2. Take the train from Roma Termini to IserniatrainRe
    6h 20m
    €57–129
  7. Train to Milano Malpensa Airport, fly to Naples Airport, train

    1. Take the train from Milano Porta Garibaldi to Malpensa Aeroporto T1train
    2. Fly from Milano Malpensa Airport (MXP) to Naples Airport (NAP)planeMXP - NAP
    3. Take the train from Napoli Centrale to Iserniatrain
    6h 31m
    €42–183
  8. Bus to Il Caravaggio International Airport, fly to Naples Airport, train

    1. Take the bus from Piazza Luigi di Savoia to Bergamo Airport Bus Stationbus
    2. Fly from Il Caravaggio International Airport (BGY) to Naples Airport (NAP)planeBGY - NAP
    3. Take the train from Napoli Centrale to Iserniatrain
    6h 40m
    €58–215
  9. Fly Milan Linate Airport to Fiumicino International Airport, train

    1. Fly from Milan Linate Airport (LIN) to Fiumicino International Airport (FCO)planeLIN - FCO
    2. Take the train from Roma Termini to Iserniatrain
    6h 12m
    €61–195
  10. Train to Milano Malpensa Airport, fly to Foggia Gino Lisa Airport, bus

    1. Take the train from Milano Porta Garibaldi to Malpensa Aeroporto T1train
    2. Fly from Milano Malpensa Airport (MXP) to Foggia Gino Lisa Airport (FOG)planeMXP - FOG
    3. Take the bus from Foggia to Iserniabus
    6h 50m
    €82–249
  11. Train to Milano Malpensa Airport, fly to Abruzzo Airport, bus

    1. Take the train from Milano Porta Garibaldi to Malpensa Aeroporto T1train
    2. Fly from Milano Malpensa Airport (MXP) to Abruzzo Airport (PSR)planeMXP - PSR
    3. Take the bus from Pescara to Iserniabus
    7h 48m
    €42–222

Milan to Isernia by train

Calendar35Weekly Trains
Duration6h 1mAverage Duration
Ticket€57Cheapest Price
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Questions & Answers

What companies run services between Milan, Italy and Isernia, Italy?

You can take a train from Milan Rogoredo to Isernia via Roma Termini in around 6h 1m. Alternatively, you can take a bus from Milano, San Donato M3 to Isernia via San Salvo Marina in around 10h 51m.

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Bus operators

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