The average bus between Isernia and Brussels takes 28h 23m and the fastest bus takes 28h 5m. The bus runs, on average, 6 times per week from Isernia to Brussels. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 6 times a week between Isernia and Brussels. The earliest departure is at 11:35 AM in the morning, and the last departure from Isernia is at 11:35 AM which arrives into Brussels at 5:30 PM. All services require a transfer at Roma, Autostazione Tiburtina and take an average of 28h 23m. The schedules shown below are for the next available departures.
Want to know about travelling from Isernia to Brussels? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Isernia to Brussels. However, there are services departing from Isernia station and arriving at Brussels station via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 28h 23m.
Isernia to Brussels bus services, operated by FlixBus, depart from Isernia station.
Isernia to Brussels bus services, operated by FlixBus, arrive at Brussels - Midi Train Station.
Book your Isernia to Brussels bus tickets online with FlixBus and BlaBlaCar Bus.
The distance between Isernia and Brussels is 1,277.2 km. The road distance is 1,942 km.
You can take a bus from Isernia to Brussels - Midi Train Station via Roma, Autostazione Tiburtina and Paris - Bercy-Seine Bus Station in around 27h 53m.