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How to get fromIsernia to Brusselsby train, plane, train (Trenitalia, TGV, Eurostar), bus, night train, car or car train

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There are 12 ways to get from Isernia to Brussels by train, plane, train (Trenitalia, TGV, Eurostar), bus, night train, car, or car train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Naples Airport, fly to Brussels Airport

    best
    1. Take the train from Isernia to Casertatrain train
    2. Fly from Naples Airport (NAP) to Brussels Airport (BRU)plane plane NAP - BRU
    7h 21m
    €80–218

  2. Train to Fiumicino International Airport, fly to Brussels Airport

    cheapest
    1. Take the train from Isernia to Roma Terminitrain train
    2. Fly from Fiumicino International Airport (FCO) to Brussels Airport (BRU)plane plane FCO - BRU
    7h 38m
    €65–201

  3. Train

    1. Take the train from Isernia to Roma Terminitrain train Re
    2. Take the train from Roma Termini to Milano Centraletrain train
    3. Take the train from Milano Centrale to Torino Porta di Susatrain train
    4. Take the train from Torino Porta Susa to Aeroport Cdg2 Tgv Roissytrain train Tgv
    5. Take the train from Aeroport Cdg2 Tgv Roissy to Brussel-Zuid / Bruxelles-Miditrain train Tgv
    16h 32m
    €307–604

  4. Bus

    1. Take the bus from Isernia to Roma, Autostazione Tiburtinabus bus
    2. Take the bus from Roma, Autostazione Tiburtina to Paris, Quai de Bercy (Bercy Seine)bus bus
    3. Take the bus from Paris - Bercy-Seine Bus Station to Brussels - Midi Train Stationbus bus
    28h 39m
    €122–224

  5. Train, night train

    1. Take the train from Isernia to Roma Tiburtinatrain train Re
    2. Take the night train from Roma Tiburtina to Muenchen Ostnighttrain night train En
    3. Take the night train from Muenchen Ost to Brussels-Nordnighttrain night train Nj
    30h 8m
    €259–449

  6. Train to Naples Airport, fly to Brussels South Charleroi Airport, train

    1. Take the train from Isernia to Casertatrain train
    2. Fly from Naples Airport (NAP) to Brussels South Charleroi Airport (CRL)plane plane NAP - CRL
    3. Take the train from Luttre to Bruxelles-Centraltrain train
    8h 29m
    €75–243

  7. Train to Roma Ciampino Airport, fly to Brussels South Charleroi Airport, train

    1. Take the train from Isernia to Ciampinotrain train
    2. Fly from Roma Ciampino Airport (CIA) to Brussels South Charleroi Airport (CRL)plane plane CIA - CRL
    3. Take the train from Luttre to Bruxelles-Centraltrain train
    10h 46m
    €80–279

  8. Train to Naples Airport, fly to Amsterdam Airport Schiphol, train

    1. Take the train from Isernia to Casertatrain train
    2. Fly from Naples Airport (NAP) to Amsterdam Airport Schiphol (AMS)plane plane NAP - AMS
    3. Take the train from Schiphol Airport Train Station to Brussel-Zuidtrain train
    9h 20m
    €103–293

  9. Bus, train to Abruzzo Airport, fly to Brussels South Charleroi Airport, train

    1. Take the bus from Isernia to Montenero Bivio SS16bus bus
    2. Take the train from Montenero-Petacciato to Pescara Porta Nuovatrain train
    3. Fly from Abruzzo Airport (PSR) to Brussels South Charleroi Airport (CRL)plane plane PSR - CRL
    4. Take the train from Luttre to Bruxelles-Centraltrain train
    9h 50m
    €67–205

  10. Bus via Bologna

    1. Take the bus from Isernia to Chieti Scalobus bus
    2. Take the bus from Pescara hotel Dragonara to Bolognabus bus
    3. Take the bus from Bologna to Brussels-North Stationbus bus
    28h 55m

  11. Drive 1,580.7 km

    1. Drive from Isernia to Brusselscar car 1,580.7 km
    16h 11m
    €248–358

  12. Drive, car train

    1. Drive from Isernia to Villach Hbfcar car
    2. Take the car train from Villach Hbf to Düsseldorf Hbfcartrain train
    3. Drive from Düsseldorf Hbf to Brusselscar car
    18h 1m
    €264–1,238

Isernia to Brussels by train

Calendar3Weekly Trains
Duration16h 32mAverage Duration
Ticket€307Cheapest Price
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Questions & Answers

What companies run services between Isernia, Italy and Brussels, Belgium?

You can take a train from Isernia to Brussel-Zuid / Bruxelles-Midi via Roma Termini, Milano Centrale, Torino Porta Susa, and Aeroport Cdg2 Tgv Roissy in around 16h 32m. Alternatively, you can take a bus from Isernia to Brussels - Midi Train Station via Roma, Autostazione Tiburtina, Paris, Quai de Bercy (Bercy Seine), and Paris - Bercy-Seine Bus Station in around 28h 39m.

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