The bus between Rome and Isernia takes 2h 10m. The bus service runs several times per day from Rome to Isernia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Rome and Isernia. The earliest departure is at 11:15 AM in the morning, and the last departure from Rome is at 9:00 PM which arrives into Isernia at 11:10 PM. All services run direct with no transfers required, and take on average 2h 10m. The schedules shown below are for the next available departures.
Want to know about travelling from Rome to Isernia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
Yes, there is a direct bus departing from Rome station and arriving at Isernia station. Services depart 4 times a day, and operate Twice daily. The journey takes approximately 2h 10m.
Rome to Isernia bus services, operated by ATM Azienda di Trasporti Molisana S.p.A., depart from Roma, Autostazione Tiburtina station.
Rome to Isernia bus services, operated by ATM Azienda di Trasporti Molisana S.p.A., arrive at Isernia station.
Book your Rome to Isernia bus tickets online with ATM Azienda di Trasporti Molisana S.p.A. and FlixBus.
The distance between Rome and Isernia is 147.7 km. The road distance is 173 km.
ATM Azienda di Trasporti Molisana S.p.A. operates a bus from Roma, Autostazione Tiburtina to Isernia 3 times a day. Tickets cost €8–13 and the journey takes 2h 10m. FlixBus also services this route once daily.