The average bus between Rome Termini and Isernia takes 3h 35m and the fastest bus takes 2h 25m. The bus service runs several times per day from Rome Termini to Isernia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Rome Termini and Isernia. The earliest departure is at 10:35 AM in the morning, and the last departure from Rome Termini is at 4:20 PM which arrives into Isernia at 8:40 PM. All services require a transfer, and take on average 3h 35m. The schedules shown below are for the next available departures.
Want to know about travelling from Rome Termini to Isernia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Rome Termini to Isernia. However, there are services departing from Roma, Autostazione Tiburtina station and arriving at Isernia station via Isernia station. The journey, including transfers, takes approximately 3h 35m.
Rome Termini to Isernia bus services, operated by ATM Azienda di Trasporti Molisana S.p.A., depart from Roma, Autostazione Tiburtina station.
Rome Termini to Isernia bus services, operated by ATM Azienda di Trasporti Molisana S.p.A., arrive at Isernia station.
The distance between Rome Termini and Isernia is 147.7 km. The road distance is 173 km.
ATM Azienda di Trasporti Molisana S.p.A. operates a bus from Roma, Autostazione Tiburtina to Isernia 3 times a day. Tickets cost €8–13 and the journey takes 2h 10m. FlixBus also services this route once daily.