Bus Rome, Termini to Isernia from €13 | Tickets & Timetables

Trip Overview

The average bus between Rome, Termini and Isernia takes 2h 44m and the fastest bus takes 2h 35m. The bus service runs several times per day from Rome, Termini to Isernia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2h 44m
Duration: 179 km
Distance: €13
Average price: 4 times a day
Frequency

Bus

best

Take the bus from Roma, Autostazione Tiburtina to Iserniabus Rome Tiburtina

3h 34m

€9–28

Rome, Termini to Isernia bus times

Buses run 4 times a day between Rome, Termini and Isernia. The earliest departure is at 10:40 AM in the morning, and the last departure from Rome, Termini is at 8:32 PM which arrives into Isernia at 11:10 PM. All services require a transfer, and take on average 2h 44m. The schedules shown below are for the next available departures.

Departing Thursday, April 30, 2026

2:18 PM → 5:15 PM
2h 56m • 1 change
3:59 PM → 6:40 PM
2h 40m • 1 change
5:49 PM → 8:40 PM
2h 50m • 1 change

Departing Friday, May 1, 2026

10:48 AM → 1:25 PM
2h 36m • 1 change
2:18 PM → 5:00 PM
2h 41m • 1 change
4:04 PM → 6:40 PM
2h 35m • 1 change
5:55 PM → 8:40 PM
2h 44m • 1 change

Departing Saturday, May 2, 2026

10:48 AM → 1:25 PM
2h 36m • 1 change
2:09 PM → 5:00 PM
2h 51m • 1 change
3:53 PM → 6:40 PM
2h 46m • 1 change
5:50 PM → 8:40 PM
2h 50m • 1 change

Departing Sunday, May 3, 2026

2:18 PM → 5:00 PM
2h 41m • 1 change
3:21 PM → 6:10 PM
2h 48m • 1 change
5:55 PM → 8:40 PM
2h 44m • 1 change
8:32 PM → 11:10 PM
2h 37m • 1 change

Departing Monday, May 4, 2026

10:40 AM → 1:25 PM
2h 44m • 1 change
2:18 PM → 5:00 PM
2h 41m • 1 change
3:59 PM → 6:40 PM
2h 40m • 1 change
5:49 PM → 8:40 PM
2h 50m • 1 change

Departing Tuesday, May 5, 2026

10:40 AM → 1:25 PM
2h 44m • 1 change
2:18 PM → 5:00 PM
2h 41m • 1 change
3:59 PM → 6:40 PM
2h 40m • 1 change
5:49 PM → 8:40 PM
2h 50m • 1 change

Departing Wednesday, May 6, 2026

10:40 AM → 1:25 PM
2h 44m • 1 change
2:18 PM → 5:00 PM
2h 41m • 1 change
3:59 PM → 6:40 PM
2h 40m • 1 change
5:49 PM → 8:40 PM
2h 50m • 1 change

Frequently asked questions

Want to know about travelling from Rome, Termini to Isernia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.