Bus Siena to Lazio from €25 | Tickets & Timetables

Trip Overview

The average bus between Siena and Lazio takes 3h 21m and the fastest bus takes 2h 59m. The bus service runs several times per day from Siena to Lazio. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

3h 21m
Duration: 234 km
Distance: €25
Average price: Every 3 hours
Frequency

Bus

best

Take the bus from Siena to Roma, Autostazione Tiburtinabus 1520 / ...

3h 17m

€17–34

Siena to Lazio bus times

Buses run every 3 hours between Siena and Lazio. The earliest departure is at 5:35 AM in the morning, and the last departure from Siena is at 10:25 PM which arrives into Lazio at 1:36 AM. All services require a transfer, and take on average 3h 21m. The schedules shown below are for the next available departures.

Departing Thursday, May 28, 2026

10:25 PM → 1:37 AM
Arrives next day
3h 12m • 1 change

Departing Friday, May 29, 2026

5:35 AM → 9:10 AM
3h 35m • 1 change
7:00 AM → 10:23 AM
3h 23m • 1 change
8:45 AM → 12:06 PM
3h 21m • 1 change
10:45 AM → 2:02 PM
3h 17m • 1 change
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Departing Saturday, May 30, 2026

5:35 AM → 9:04 AM
3h 29m • 1 change
7:00 AM → 10:28 AM
3h 28m • 1 change
8:45 AM → 11:53 AM
3h 8m • 1 change
10:45 AM → 2:02 PM
3h 17m • 1 change
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Departing Sunday, May 31, 2026

5:35 AM → 9:08 AM
3h 33m • 1 change
7:00 AM → 10:28 AM
3h 28m • 1 change
8:45 AM → 11:52 AM
3h 7m • 1 change
10:45 AM → 1:58 PM
3h 13m • 1 change
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Departing Monday, June 1, 2026

5:35 AM → 9:10 AM
3h 35m • 1 change
7:00 AM → 10:23 AM
3h 23m • 1 change
8:45 AM → 12:06 PM
3h 21m • 1 change
10:45 AM → 2:02 PM
3h 17m • 1 change
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Departing Tuesday, June 2, 2026

5:35 AM → 9:08 AM
3h 33m • 1 change
7:00 AM → 10:28 AM
3h 28m • 1 change
8:45 AM → 11:52 AM
3h 7m • 1 change
10:45 AM → 1:58 PM
3h 13m • 1 change
Show more

Departing Wednesday, June 3, 2026

5:35 AM → 9:10 AM
3h 35m • 1 change
7:00 AM → 10:23 AM
3h 23m • 1 change

Frequently asked questions

Want to know about travelling from Siena to Lazio? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.