Pisa to Lyon Buses

Pisa to Lyon buses

Travel from

Search accommodation with Expedia

Trip Overview

The average bus between Pisa and Lyon takes 13h 23m and the fastest bus takes 12h 20m. The bus service runs several times per day from Pisa to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

13h 23m
Duration: 832 km
Distance: €69
Average price: 4 times a day
Frequency

Bus

best

Take the bus from Pisa to Florence Villa Constanza Bus Stationbus 443 / ...
Take the bus from Florence Villa Constanza Bus Station to Lyonbus 1501 / ...

13h 15m

€43–107

Pisa to Lyon bus times

Buses run 4 times a day between Pisa and Lyon. The earliest departure is at 5:45 AM in the morning, and the last departure from Pisa is at 11:00 PM which arrives into Lyon at 12:55 PM. All services require a transfer, and take on average 13h 23m. The schedules shown below are for the next available departures.

Departing Wednesday, October 7, 2026

6:10 PM → 8:45 AM
Arrives next day
14h 35m • 1 change

Departing Thursday, October 8, 2026

8:15 AM → 9:30 PM
13h 15m • 1 change
1:00 PM → 1:20 AM
Arrives next day
12h 20m • 1 change
6:10 PM → 8:45 AM
Arrives next day
14h 35m • 1 change
11:00 PM → 12:55 PM
Arrives next day
13h 55m • 1 change

Departing Friday, October 9, 2026

5:45 AM → 6:10 PM
12h 25m • 1 change
8:15 AM → 9:30 PM
13h 15m • 1 change
1:00 PM → 1:20 AM
Arrives next day
12h 20m • 1 change
6:10 PM → 8:45 AM
Arrives next day
14h 35m • 1 change
Show more

Departing Saturday, October 10, 2026

5:45 AM → 6:10 PM
12h 25m • 1 change
8:15 AM → 9:30 PM
13h 15m • 1 change
1:00 PM → 1:20 AM
Arrives next day
12h 20m • 1 change
6:10 PM → 8:45 AM
Arrives next day
14h 35m • 1 change
Show more

Departing Sunday, October 11, 2026

5:45 AM → 6:10 PM
12h 25m • 1 change
8:15 AM → 9:30 PM
13h 15m • 1 change
1:00 PM → 1:20 AM
Arrives next day
12h 20m • 1 change
6:10 PM → 7:05 AM
Arrives next day
12h 55m • 1 change
Show more

Departing Monday, October 12, 2026

5:45 AM → 6:10 PM
12h 25m • 1 change
8:15 AM → 9:30 PM
13h 15m • 1 change
1:00 PM → 1:20 AM
Arrives next day
12h 20m • 1 change
6:10 PM → 9:45 AM
Arrives next day
15h 35m • 1 change
Show more

Departing Tuesday, October 13, 2026

5:45 AM → 6:10 PM
12h 25m • 1 change
8:15 AM → 9:30 PM
13h 15m • 1 change
6:10 PM → 9:45 AM
Arrives next day
15h 35m • 1 change

Frequently asked questions

Want to know about travelling from Pisa to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Trip Overview

Bus