The average bus between Pisa and Rome takes 5h 10m and the fastest bus takes 4h 35m. The bus service runs several times per day from Pisa to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a day between Pisa and Rome. The earliest departure is at 12:25 AM at night, and the last departure from Pisa is at 10:00 PM which arrives into Rome at 2:35 AM. All services run direct with no transfers required, and take on average 5h 10m. The schedules shown below are for the next available departures.
Arrives next day
Want to know about travelling from Pisa to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
Yes, there is a direct bus departing from Pisa station and arriving at Rome station. Services depart 5 times a day, and operate Once daily. The journey takes approximately 5h 10m.
Pisa to Rome bus services, operated by FlixBus, depart from Pisa station.
Pisa to Rome bus services, operated by FlixBus, arrive at Roma, Autostazione Tiburtina station.
Book your Pisa to Rome bus tickets online with FlixBus and AutoLinee Moretti.
The distance between Pisa and Rome is 263.9 km. The road distance is 336 km.
FlixBus operates a bus from Pisa to Roma, Autostazione Tiburtina 4 times a day. Tickets cost €22–40 and the journey takes 4h 45m. AutoLinee Moretti also services this route 3 times a week.